Rv0081



Type
protein_coding
Name
Rv0081
Locus Name

Rv0081

Product

Probable transcriptional regulatory protein

Functional Category

Regulatory proteins

Location
89575..89919 (+ strand)
Gene Length
344 bp
Nucleotides
TGGAGTCCGAACCGCTGTACAAGCTCAAGGCGGAGTTCTTCAAAACCCTTGCGCATCCGGCGCGGATCAGGATTTTGGAGCTGCTGGTCGAGCGGGACCGTTCGGTCGGTGAGTTGCTGTCCTCGGACGTCGGCCTGGAGTCGTCGAACCTGTCCCAGCAGCTGGGTGTGCTACGCCGGGCGGGTGTTGTCGCGGCACGTCGTGACGGCAACGCGATGATCTATTCGATTGCCGCACCCGATATCGCCGAGCTGCTGGCGGTGGCACGCAAGGTGCTGGCCAGGGTGCTCAGCGACCGGGTGGCGGTGCTAGAGGACCTCCGCGCCGGCGGCTCGGCCACGTAA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Unknown
Family

Unknown

GO
InterPro

UniProt
P9WMI7
GenBank
Rv0081
EnsemblBacteria
Rv0081
Mycobrowser
Rv0081


6JMI
Summary
Name
Uncharacterized HTH-type transcriptional regulator Rv0081
Family
Unknown
Protein Sequence
MESEPLYKLKAEFFKTLAHPARIRILELLVERDRSVGELLSSDVGLESSNLSQQLGVLRRAGVVAARRDGNAMIYSIAAPDIAELLAVARKVLARVLSDRVAVLEDLRAGGSAT
Mass
12,356 Da
Length
114 Aa

Rv0081 doesn't seem to be a targeted by any drug.


Rv0081 doesn't seem to be involved in any pathway.


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.
Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin.
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7534-9. doi: 10.1073/pnas.121172498.
Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program.
J Exp Med. 2003 Sep 1;198(5):705-13. doi: 10.1084/jem.20030205.
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection.
Cell Host Microbe. 2008 May 15;3(5):323-30. doi: 10.1016/j.chom.2008.03.007.
Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon.
J Biol Chem. 2008 Jun 27;283(26):18032-9. doi: 10.1074/jbc.M802274200. Epub 2008 Apr 9.
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.
Clin Vaccine Immunol. 2009 Aug;16(8):1203-12. doi: 10.1128/CVI.00111-09. Epub 2009 Jun 24.