htdZ
- Type
- protein_coding
- Name
- htdZ
- Locus Name
-
Rv0130
- Product
-
Probable 3-hydroxyl-thioester dehydratase
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 157847..158302 (+ strand)
- Gene Length
- 455 bp
- Nucleotides
-
TGCGCACCTTCGAGTCGGTCGCCGACCTGGCCGCCGCCGCGGGCGAAAAGGTCGGGCAGAGCGACTGGGTGACCATCACCCAGGAAGAGGTCAATCTGTTCGCCGACGCAACGGGTGATCACCAGTGGATCCACGTCGACCCGGAACGGGCCGCTGCGGGTCCCTTTGGCACCACCATCGCGCACGGATTCATGACCCTGGCGTTGCTCCCGCGCCTGCAACACCAGATGTACACCGTCAAGGGCGTCAAGCTGGCAATCAACTACGGCCTGAACAAGGTTCGCTTCCCGGCACCAGTACCCGTCGGCTCGCGGGTGCGTGCGACGAGCTCGCTGGTCGGTGTCGAGGATCTGGGCAACGGCACCGTGCAGGCGACGGTGTCGACGACCGTCGAGGTCGAGGGATCGGCCAAGCCGGCGTGTGTGGCCGAAAGCATCGTGCGCTACGTCGCCTGA
- Drug Resistance
- Mutations
- Function
- May be involved in the hydration of fatty acids for production of polyhydroxylalkanoates. {ECO:0000269|PubMed:16963641}.
- Family
-
Enoyl-CoA hydratase/isomerase family
- GO
-
- enoyl-CoA hydratase activity GO:0004300 molecular_function
- 3-hydroxyacyl-CoA dehydratase activity GO:0018812 molecular_function
- fatty acid biosynthetic process GO:0006633 biological_process
- InterPro
2C2I
- Name
- Probable enoyl-CoA hydratase 1 (EC 4.2.1.17) (N-related protein) (Nodulation protein)
- Family
- Enoyl-CoA hydratase/isomerase family
- Protein Sequence
-
MRTFESVADLAAAAGEKVGQSDWVTITQEEVNLFADATGDHQWIHVDPERAAAGPFGTTIAHGFMTLALLPRLQHQMYTVKGVKLAINYGLNKVRFPAPVPVGSRVRATSSLVGVEDLGNGTVQATVSTTVEVEGSAKPACVAESIVRYVA
- Mass
- 16,007 Da
- Length
- 151 Aa
Summary
Rv0130 doesn't seem to be a targeted by any drug.
Rv0130 doesn't seem to be involved in any pathway.
- Structure and function of Rv0130, a conserved hypothetical protein from Mycobacterium tuberculosis.
- Protein Sci. 2006 Oct;15(10):2300-9. doi: 10.1110/ps.062309306. Epub 2006 Sep 8.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.