php
- Type
- protein_coding
- Name
- php
- Locus Name
-
Rv0230c
- Product
-
Probable phosphotriesterase Php (parathion hydrolase) (PTE) (aryldialkylphosphatase) (paraoxonase) (a-esterase) (aryltriphosphatase) (paraoxon hydrolase)
- Functional Category
-
Lipid metabolism
- Location
- 274983..275963 (- strand)
- Gene Length
- 980 bp
- Nucleotides
-
GTGCCAGAACTAAATACCGCTCGCGGACCCATCGACACCGCTGATCTCGGCGTCACGCTGATGCACGAGCACGTCTTCATCATGACCACCGAGATTGCGCAGAACTACCCGGAAGCCTGGGGCGACGAGGACAAGCGGGTGGCCGGCGCCATCGCCCGGCTAGGCGAACTCAAGGCCCGCGGCGTGGACACCATCGTCGACCTCACGGTGATCGGGCTGGGCCGATACATCCCGCGCATCGCCCGGGTGGCCGCGGCCACCGAGCTGAACATCGTCGTGGCCACCGGCTTGTACACCTACAACGACGTCCCGTTCTACTTCCACTACCTCGGGCCGGGCGCACAGCTGGACGGCCCGGAGATCATGACCGACATGTTCGTCCGCGACATCGAGCACGGCATCGCCGACACCGGCATCAAGGCGGGAATCCTCAAGTGCGCCACCGACGAACCCGGCCTCACCCCTGGTGTCGAGCGGGTGTTGCGCGCGGTCGCCCAAGCACACAAACGCACCGGGGCGCCGATCTCCACCCACACCCACGCCGGGCTGCGGCGCGGCCTTGACCAGCAACGCATCTTCGCCGAGGAGGGGGTGGACCTGAGCCGGGTGGTTATCGGACACTGCGGCGACAGCACCGACGTCGGCTACCTGGAAGAGCTCATCGCCGCCGGCTCCTACCTCGGGATGGACCGGTTCGGCGTCGACGTGATCTCACCGTTTCAGGACCGGGTGAACATCGTGGCCCGAATGTGCGAGCGCGGCCATGCCGACAAGATGGTGCTATCACACGACGCCTGCTGCTATTTCGACGCGCTTCCCGAGGAGCTGGTGCCGGTGGCGATGCCGAATTGGCATTACCTCCACATCCACAACGACGTCATCCCCGCACTGAAGCAGCACGGCGTCACCGACGAGCAGCTGCACACCATGCTCGTCGACAACCCGCGCCGCATCTTCGAGCGGCAGGGCGGCTATCAGTG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Metallo-dependent hydrolases superfamily, Phosphotriesterase family
- GO
-
- catabolic process GO:0009056 biological_process
- zinc ion binding GO:0008270 molecular_function
- hydrolase activity, acting on ester bonds GO:0016788 molecular_function
- InterPro
4IF2
- Name
- Phosphotriesterase homology protein
- Family
- Metallo-dependent hydrolases superfamily, Phosphotriesterase family
- Protein Sequence
-
MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVAGAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCATDEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGVDLSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVARMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFERQGGYQ
- Mass
- 35,886 Da
- Length
- 326 Aa
Summary
Rv0230c doesn't seem to be a targeted by any drug.
Rv0230c doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.