Gene - combatTB X

PPE6

Type: protein_coding
Name: PPE6
Locus Name: Rv0305c
Product: PPE family protein PPE6
Functional Category: Pe/ppe
Location: 372820..375711 (- strand)
Gene Length: 2891 bp
Nucleotides: ATGGATTTCGTGGTGTCGGCGCCCGAGGTCAATTCGTTACGGATGTATCTCGGGGCCGGATCGGGGCCGATGTTGGCGGCCGCGGCGGCCTGGGACGGACTAGCCGACGAACTGGCGGTGGCGGCGTCGTGGTTTGGGTCGGTGACCTCGGGCCTGGCGGATGCGGCGTGGCGCGGCCCCGCGGCGGTTGCGATGGCGCGCGCGGTAGCCCCCTACCTGGGCTGGTTGATTTCGGCAACGGCCCAGGCTGAGCAGGCCGCCGCTCAGGCACGGGTAGCCGTGGCCACGTTCGAGGCGGCGCGGGCAGCGACGGTGCATCCGGCGATCGTCGCGGCCAACCGCGCCGTGCTGGTGTCGCTGGTGAGCTCGAATCTGCTGGGATTCAACGCTCCGGCGATCGCGGCCACCGAGGCCGCCTATGAGCGGATGTGGGCCCAGGATGTGGCCGCGATGGTTGGCTATCACGCTGGAGCGTCGGCGGCCGTCTCCGCGTTGATGCCGTTCACCCAGCAGCTGAAGAAGCTGGCGGGCCTATCGGAGCGGCTGACCAGCGCCGCGGCAGCCGCTGCCGGCCCCCCGAGCGCGGCGGGCTTCAATCTCGGCTTGGCAAACGTCGGCGCCAACAACGTGGGCAACGGAAACGTCGGCGTGTTCAACGTCGGCTTCGGCAATTTGGGCAGCTACAACCTCGGCTTTGCAAACCTGGGCAGCGACAACCTGGGTTTGGCCAACCTGGGCGGCCACAACATCGGCTTTGCGAACACCGGCAGCAACAATGTCGGCTTTGGGAATACGGGCAGCAACAATGTCGGCATCGGGCTCACCGGCAACGGACAGATCGGGTTCGGCAGCTTCAACTCGGGCAGCCACAACATCGGCCTGTTCAACTCCGGCAGCGGAAACGTCGGGTTGTTCAACTCGGGCACCGGCAATTTCGGCATCGGAAACAGCGGCACCGGAAACTTCGGCCTCGGCAACACGGGCAGCACCAACACCGGCTGGTTCAACACCGGCGACGTCAACACCGGCGGCTTCAACCCGGGCAGCTACAACACCGGGAACTTCAACACCGGCAACTACAACACCGGCAGCTTCAACGCAGGTAACTACAACACCGGCTACTTCAACACCGGCGACTACAACACTGGAGTGGCCAACACCGGCAACGTCAACACCGGCGCCTTCATCGCCGGCAACTACAGCAACGGCGTCTTGTGGCGGGGCGACTACCAAGGCCTGATCGGTGCCGATATCGCCCTCGAGATTCCCGCCATTCCGATAAACGCGCAGCTATTCAGCATGCCGATACATCAGGTGATGGTCATGCCCGGAAGCGTGATGACGATTCCGGGCATGCGTTTGCCCTTCACATCCATTGTTCCCTTCGTTGTTTACTACGGCCCGGTCGAGCTCCCGCAATCCACGCTCACCCTTCCCACGGTGACGATCACCGTGGGCGGACCAACCACCACGATCGACGGCAACCTCACCGGCATGGTGGGGGGCGTCAGCATCCCGCTCATCAAGATTCCGGCGGCCCCGGGCTTCGGGAACTCGACCACCAGCCCGTCGTCGGGCTTCTTCAACGCTGGCGCCGGCACCGCCTCGGGCTTCGGCAACTTCGGCGGCGGCGCTTCGGGCTTTTGGAACCTGGCCTCGGCAACCTCGGGACTTTCGGGCTTCGGGAACGTCGGCGCGCTGGGATCGGGTGTAGCTAACGTTGGCAACACCATCTCGGGTCTCTACAACACGAGCACGTCGAATCTGGCGACGCCAGCCTTTAACTCCGGCCTGCTGCACCACAGCGTGGGCACCATGACCCTTAACTTCGGGTTGGCAAACGTCGGCGGCAACAATGTCGGCGGTGCAAACGCCGGAATCTTCAATGTGGGCTTGGCAAACCTGGGCGACTACAATATTGGCTTCGGCAATCTAGGCGGCGACAACCTGGGCTTCGCCCACGCGGGCAGCTACAACATCGGCTTTGCGAACACCGGCAGCAATAATCTTGGCTTCGCGAACACGGGTGACAACAATATCGGTTTTGCGAATATCGGCAGCAACAATATCGGGATCGGGCTCACCGGCAGCGGCCAGATCGGGTTCGGCAGCCTGAACTCGGGCAGCCACAATATCGGCTTGTTCAACTCGGGTGACGGAAACATCGGATTGTTCAACTCGGGCAGCGGAAACTTCGGGATAGGAAACGCGGGCACCGGAAACTGGGGCATCGGAAACTCGGGCGCCGGAAACTTCGGCATCGGGAACGCGGGCAGCACCAACACGGGCTTGTTCAACTCCGGAGACCTCAACACGGGTAGCTTGAACCCGGGCAGCTATAACACCGGCAGCGTCAACACCGGCAGCGTCAACACCGGTGGCTTCAATGCAGGTAACTACAACACCGGCTACTTCAACACCGGCGACTTACAACACCGGCATGGCGAACACCGGCAATATCAACACCGGCGCTTTCATCTCCGGCAACCACAGCAACGGCCTTCTGTGGCGGGGCGACAACCAGGGTCTGATCGACCTCGCCATCGGCGTCGACATTCCCGAAATCCCGATTGTGAGCGTCGACGTGAATATCCCGATTCACATACCGATCACCGCCAGCTTCACGGACATCGTATACAGCGGGCTCGATCTTCCACCGAACACAGCCGTCACTGTTATTTTTTTCGGACCCGTCGATATCGACCCCTTCACCGTCCCAGTGATACGGATAACCGGTCCCACACCTGTGGTCATGGTGGGTGGACCCACTACCGCGATCAATATCGGCGCCACTGTGGTCGTCGACGCCATCAACATCCCGATTATCCATATTCCAGCGACTCCAGGCTTCGGCAACTCGACCGGCGGACTGTCGTCGGGCTTCTTCAATA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PPE family

GO

cell wall GO:0005618 cellular_component
cytosol GO:0005829 cellular_component
plasma membrane GO:0005886 cellular_component

InterPro

UniProt: Q6MX48
GenBank: Rv0305c
EnsemblBacteria: Rv0305c
Mycobrowser: Rv0305c

Summary

Name: PPE family protein PPE6
Family: Mycobacterial PPE family
Protein Sequence: MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRPLHRPSDTDNRSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVGLLQ
Mass: 98,969 Da
Length: 963 Aa

Rv0305c doesn't seem to be a targeted by any drug.

Rv0305c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.