Gene - combatTB X

PPE11

Type: protein_coding
Name: PPE11
Locus Name: Rv0453
Product: PPE family protein PPE11
Functional Category: Pe/ppe
Location: 543174..544730 (+ strand)
Gene Length: 1556 bp
Nucleotides: TGACGAGCGCACTGATATGGATGGCCTCTCCGCCGGAGGTGCATTCGGCCTTGTTGAGTAGTGGGCCGGGGCCGGGGCCGGTACTGGCCGCCGCCACAGGGTGGTCGTCACTGGGCCGTGAATACGCCGCGGTTGCTGAGGAACTCGGGGCATTGCTGGCTGCGGTGCAAGCCGGGGTGTGGCAGGGGCCCAGCGCCGAATCATTTGCTGCCGCGTGCCTGCCGTATCTGTCTTGGTTGACGCAGGCCAGCGCCGACTGCGCCGCGGCGGCTGCCCGGCTGGAGGCGGTGACCGCCGCCTACGCCGCGGCTTTGGTGGCCATGCCCACCCTGGCCGAGTTGGCGGCTAACCACGCGACCCACGGGGCCATGGTGGCGACCAATTTCTTCGGGATCAACACCATACCGATCGCGGTCAACGAGGCCGACTACGTGCGGATGTGGCTTCAGGCGGCCACCACGATGGCCACCTATCAAGCGGTCGCGGACTCGGCGGTGCGCTCGATCCCGGACAGCGTGCCTCCGCCGCGAATTCTGAAATCCAATGCCCAATCCCAACACTCGAGCTCGAATAATTCCGGGGGCGCGGACCCGGTGGACGACTTCATTGCAGAGATCTTGAAGATCATCACCGGCGGTCGCGTGATCTGGGACCCCGAAGCCGGCACTGTCAACGGCCTCCCCTATGACGCTTATACCAACCCCGGCACACTCATGTGGTGGATTGCCAGAAGTCTGGAACTTCTTCAAGACTTTCAAGAGTTCGCCAAGCTGCTGTTCACCAATCCGGTGAAGGCTTTTCAGTTCCTTGTCGACCTCATCCTGTTCGACTGGCCTACACACATGCTGCAGCTGGCTACCTGGCTGGCCGAGAACCCGCAGTTGCTGGTGGCTGCGCTCACCCCAGCCATCTCCGGACTGGGAGCGGTATCGGGGTTGGCCGGGTTGACCGGCCTAGTCCCTCAGCCCCCCGTCGTGCCCGCGCCGGCACCCGATGCGGTCGTGCCCACCGTGTTGCCACTCGCCGGGACGGCCACGCCGACTACCGCGCCGGCCAGCGCCCCGGCCGCCGGAGCGGCGCCCGGGCCCCCGGCCGGTACCGCCACTGCCACATCGGCGTCGGTGCCAACGAGCGCCGGCGGCTTTCCCCCTTACCTCGTGGGCAGCGGTCCAGGCATCGACTTCGACGCGGGGACGCCCGCCGGTTCCAGGAGAGCGCAGCCCGCCGCGGATAACGTCACGGCCGTGGCGGCAGCGCAGGTGTCGGCCCGTCATCAGGCACGTCGGCGCCGACGAGCGGCGGCGAAGGAACGTGGCAACGCCGACGAGTTCGTCGATATGGACTCCGGCCCGGCGATTCCGCCGTCGGGCGAGCGGGACGCTTGGGCGTCCAATTCGGGCGTGGGCGGGCTGGGGTTTGCCGGCACCGCAAGCAACGAGACGGTGGCAGCGCCGGCCGGATTGACCACGCTGGCCGACGATGAGTTCCAGTGTGGCCCACGGATGCCGATGCTGCCGGGCGCTTGGGACTTGGGAACTTGGGACCGCGGGGACTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PPE family

GO

extracellular region GO:0005576 cellular_component
cytosol GO:0005829 cellular_component

InterPro

UniProt: P9WI39
GenBank: Rv0453
EnsemblBacteria: Rv0453
Mycobrowser: Rv0453

Summary

Name: Uncharacterized PPE family protein PPE11
Family: Mycobacterial PPE family
Protein Sequence: MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGVWQGPSAESFAAACLPYLSWLTQASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQAVADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMWWIARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAALTPAISGLGAVSGLAGLTGLVPQPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTPAGSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNETVAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD
Mass: 52,837 Da
Length: 518 Aa

Rv0453 doesn't seem to be a targeted by any drug.

Rv0453 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.