deoC
- Type
- protein_coding
- Name
- deoC
- Locus Name
-
Rv0478
- Product
-
Probable deoxyribose-phosphate aldolase DeoC (phosphodeoxyriboaldolase) (deoxyriboaldolase)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 567222..567896 (+ strand)
- Gene Length
- 674 bp
- Nucleotides
-
TGCTCGGCCAACCGACTCGGGCGCAGTTGGCCGCGCTGGTAGACCACACCCTGCTCAAGCCTGAGACCACCCGTGCCGATGTGGCCGCGCTGGTCGCCGAAGCCGCCGAACTCGGCGTCTACGCGGTCTGCGTGTCGCCGTCGATGGTGCCAGTTGCGGTCCAAGCCGGTGGTGTGCGGGTTGCGGCGGTGACGGGCTTCCCGTCGGGCAAGCACGTGTCCTCGGTCAAGGCGCATGAGGCGGCTGCGGCCCTGGCATCCGGCGCCAGTGAGATCGACATGGTCATCGACATCGGGGCTGCGCTGTGCGGTGACATCGACGCAGTGCGCTCCGACATCGAGGCGGTGCGTGCCGCTGCGGCCGGGGCTGTGCTCAAGGTGATCGTGGAGTCGGCGGTGCTGTTGGGACAGTCAAACGCGCACACGTTGGTGGATGCGTGTCGTGCCGCCGAGGATGCCGGTGCCGACTTCGTCAAAACCTCGACTGGGTGTCATCCGGCCGGCGGGGCCACGGTGCGTGCCGTCGAGCTGATGGCCGAGACGGTCGGCCCTCGGCTAGGGGTCAAAGCCAGCGGTGGGATCCGCACCGCCGCCGACGCGGTCGCGATGCTCAACGCCGGTGCCACCAGGTTGGGCCTGTCCGGCACCCGGGCGGTGCTCGATGGGCTCAGCTGA
- Drug Resistance
- Mutations
- Function
- Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. {ECO:0000255|HAMAP-Rule:MF_00114}.
- Family
-
DeoC/FbaB aldolase family, DeoC type 1 subfamily
- GO
-
- deoxyribose phosphate catabolic process GO:0046386 biological_process
- deoxyribonucleotide catabolic process GO:0009264 biological_process
- cytoplasm GO:0005737 cellular_component
- deoxyribose-phosphate aldolase activity GO:0004139 molecular_function
- carbohydrate catabolic process GO:0016052 biological_process
- InterPro
Summary
- Name
- Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)
- Family
- DeoC/FbaB aldolase family, DeoC type 1 subfamily
- Protein Sequence
-
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
- Mass
- 22,068 Da
- Length
- 224 Aa
Rv0478 doesn't seem to be a targeted by any drug.
Rv0478 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
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- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.