gpdA1
- Type
- protein_coding
- Name
- gpdA1
- Locus Name
-
Rv0564c
- Product
-
Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA1 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) (NAD(P)H-dependent dihydroxyacetone-phosphate reductase)
- Functional Category
-
Lipid metabolism
- Location
- 654924..655949 (- strand)
- Gene Length
- 1025 bp
- Nucleotides
-
ATGGCAGCCAACAAGCGCGAACCCAAAGTCGTTGTCCTCGGCGGCGGTTCCTGGGGCACCACCGTCGCCTCCATCTGTGCGCGCCGCGGACCAACCTTGCAGTGGGTGCGCTCGGCGGTCACCGCGCAGGACATCAACGACAACCACCGCAATAGCCGATACCTCGGCAACGACGTGGTGCTCAGCGACACCCTGCGCGCCACCACAGACTTCACCGAGGCCGCCAACTGCGCCGACGTCGTCGTCATGGGGGTGCCCTCGCACGGTTTCCGCGGAGTGCTTGTCGAGCTGAGCAAAGAGCTGCGACCCTGGGTGCCAGTGGTGTCCCTGGTCAAGGGGCTCGAACAGGGCACCAATATGCGGATGTCGCAGATCATCGAGGAGGTACTGCCCGGTCATCCGGCAGGCATCCTGGCCGGCCCGAACATCGCCCGCGAGGTGGCCGAGGGCTACGCGGCCGCGGCGGTGCTGGCCATGCCCGACCAGCACCTGGCGACCCGGCTATCAGCAATGTTTCGCACCCGGCGCTTCCGCGTGTACACAACTGACGACGTCGTCGGTGTCGAGACGGCGGGCGCCCTCAAGAACGTCTTCGCCATCGCGGTCGGGATGGGCTATTCGCTGGGTATCGGCGAAAACACCCGCGCCCTGGTGATCGCCCGCGCGCTGCGCGAGATGACGAAGCTGGGTGTGGCAATGGGTGGGAAAAGCGAAACGTTCCCCGGACTGGCCGGTCTCGGCGACCTGATCGTCACCTGCACCAGCCAACGCAGCCGCAACCGGCATGTGGGCGAACAACTCGGCGCAGGCAAGCCGATCGACGAAATCATCGCATCGATGAGCCAGGTCGCCGAGGGCGTCAAAGCTGCCGGTGTGGTGATGGAGTTCGCCAACGAGTTCGGGCTGAACATGCCGATCGCCCGCGAGGTCGACGCCGTCATCAACCATGGTTCGACGGTGGAGCAGGCGTATAGAGGCTTGATCGCCGAGGTCCCCGGACACGAGGTGCACGGCTCGGGGTTTTA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
NAD-dependent glycerol-3-phosphate dehydrogenase family
- GO
-
- glycerol-3-phosphate catabolic process GO:0046168 biological_process
- glycerol-3-phosphate biosynthetic process GO:0046167 biological_process
- glycerol-3-phosphate dehydrogenase complex GO:0009331 cellular_component
- glycerol-3-phosphate metabolic process GO:0006072 biological_process
- phospholipid biosynthetic process GO:0008654 biological_process
- carbohydrate metabolic process GO:0005975 biological_process
- cytosol GO:0005829 cellular_component
- glycerol-3-phosphate dehydrogenase [NAD(P)+] activity GO:0047952 molecular_function
- glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367 molecular_function
- NAD binding GO:0051287 molecular_function
- glycerophospholipid metabolic process GO:0006650 biological_process
- InterPro
Summary
- Name
- Probable glycerol-3-phosphate dehydrogenase 2 [NAD(P)+] (EC 1.1.1.94) (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2)
- Family
- NAD-dependent glycerol-3-phosphate dehydrogenase family
- Protein Sequence
-
MAANKREPKVVVLGGGSWGTTVASICARRGPTLQWVRSAVTAQDINDNHRNSRYLGNDVVLSDTLRATTDFTEAANCADVVVMGVPSHGFRGVLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVETAGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGKSETFPGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMSQVAEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF
- Mass
- 36,153 Da
- Length
- 341 Aa
Rv0564c doesn't seem to be a targeted by any drug.
-
-
Glycerophospholipid metabolism mtu00564
mtu00564PATHWAY_MAP mtu00564 Glycerophospholipid metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.