Gene - combatTB X

mce2D

Type: protein_coding
Name: mce2D
Locus Name: Rv0592
Product: Mce-family protein Mce2D
Functional Category: Virulence, detoxification, adaptation
Location: 690501..692027 (+ strand)
Gene Length: 1526 bp
Nucleotides: TGAGCACCATCTTCGACATCCGCAGCCTGCGACTGCCGAAACTGTCTGCAAAGGTAGTGGTCGTCGGCGGGTTGGTGGTGGTCTTGGCGGTCGTGGCCGCTGCGGCCGGCGCGCGGCTCTACCGGAAACTGACTACCACTACCGTGGTCGCGTATTTCTCTGAGGCGCTCGCGCTGTACCCAGGAGACAAAGTCCAGATCATGGGTGTGCGGGTCGGTTCTATCGACAAGATCGAGCCGGCCGGCGACAAGATGCGAGTCACGTTGCACTACAGCAACAAATACCAGGTGCCGGCCACGGCTACCGCGTCGATCCTCAACCCCAGCCTGGTGGCCTCGCGCACCATCCAGCTGTCACCGCCGTACACCGGCGGCCCGGTCTTGCAAGACGGCGCGGTGATCCCAATCGAGCGCACCCAGGTGCCCGTCGAGTGGGATCAGTTGCGCGATTCCATCAATGGGATCCTCCGCCAGCTCGGCCCGACGGAGCGGCAGCCGAAGGGGCCGTTCGGCGACCTCATCGAATCGGCCGCGGACAACCTGGCCGGCAAGGGCAGGCAGCTCAACGAAACGCTGAACAGTTTGTCGCAGGCGTTGACCGCGCTGAACGAGGGCCGGGGAGACTTCGTTGCGATCACGCGAAGCCTGGCGCTATTTGTCAGCGCGCTCTACCAGAATGATCAACAGTTCGTTGCGCTCAACGAAAACCTTGCCGAGTTCACCGACTGGTTCACCAAATCCGACCATGACTTGGCCGACACGGTGGAACGGATCGACGACGTTCTCGGCACCGTCCGAAAGTTCGTGAGCGACAACAGATCCGTGCTGGCTGCCGATGTCAACAACCTCGCCGACGCGACCACTACACTAGTGCAACCCGAGCCGCGGGACGGTCTGGAAACCGCGTTGCACGTGTTGCCGACCTACGCCAGCAACTTCAACAACCTTTACTATCCACTGCACAGCTCTCTGGTGGGCCAGTTCGTGTTCCCCAACTTCGCGAACCCAATTCAGCTCATTTGCAGCGCTATTCAGGCCGGCAGCCGACTCGGCTATCAGGAATCCGCCGAGCTGTGCGCGCAGTACTTGGCACCGGTTCTGGACGCTCTCAAGTTCAATTACTTGCCGTTCGGCTCAAACCCGTTCAGTTCGGCGGCCACTTTGCCCAAGGAGGTGGCTTACTCCGAGGAGCGGCTCCGCCCGCCGCCCGGGTACAAGGACACCACTGTCCCAGGGATCTTCTCGCGGGACACACCGTTTTCACACGGCAACCATGAACCGGGCTGGGTCGTTGCGCCCGGGATGCAGGGTATGCAGGTTCAGCCGTTTACCGCGAACATGCTCACCCCGGAATCGCTGGCAGAGCTGCTGGGTGGTCCGGATATTGCCCCCCCGCCGCCGGGAACCAACTTGCCCGGACCGCCGAATGCGTATGACGAGTCCAATCCGTTGCCGCCGCCGTGGTACCCGCAGCCCGCGTCCCTCCCGGCTGCGGGCGCCACAGGACAGCCAGGCCCGGGCCAGTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

growth of symbiont in host organelle GO:0044121 biological_process
growth of symbiont in host GO:0044117 biological_process

InterPro

UniProt: I6WYT7
GenBank: Rv0592
EnsemblBacteria: Rv0592
Mycobrowser: Rv0592

Summary

Name: Mce-family protein Mce2D
Family: Unknown
Protein Sequence: MSTIFDIRSLRLPKLSAKVVVVGGLVVVLAVVAAAAGARLYRKLTTTTVVAYFSEALALYPGDKVQIMGVRVGSIDKIEPAGDKMRVTLHYSNKYQVPATATASILNPSLVASRTIQLSPPYTGGPVLQDGAVIPIERTQVPVEWDQLRDSINGILRQLGPTERQPKGPFGDLIESAADNLAGKGRQLNETLNSLSQALTALNEGRGDFVAITRSLALFVSALYQNDQQFVALNENLAEFTDWFTKSDHDLADTVERIDDVLGTVRKFVSDNRSVLAADVNNLADATTTLVQPEPRDGLETALHVLPTYASNFNNLYYPLHSSLVGQFVFPNFANPIQLICSAIQAGSRLGYQESAELCAQYLAPVLDALKFNYLPFGSNPFSSAATLPKEVAYSEERLRPPPGYKDTTVPGIFSRDTPFSHGNHEPGWVVAPGMQGMQVQPFTANMLTPESLAELLGGPDIAPPPPGTNLPGPPNAYDESNPLPPPWYPQPASLPAAGATGQPGPGQ
Mass: 54,540 Da
Length: 508 Aa

Rv0592 doesn't seem to be a targeted by any drug.

ABC transporters mtu02010
mtu02010
Environmental Information Processing; Membrane transport

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.