Gene - combatTB X

mce2F

Type: protein_coding
Name: mce2F
Locus Name: Rv0594
Product: Mce-family protein Mce2F
Functional Category: Virulence, detoxification, adaptation
Location: 693237..694787 (+ strand)
Gene Length: 1550 bp
Nucleotides: TGCTGACTCGCGCTATCAAGACCCAGCTGGTGTTGTTGACGGTGTTGGCGGTCATCGCGGTGGTGGTCCTTGGTTGGTATTTCCTGCGGATACCCAGCCTGGTCGGCATCGGTCGATACACGCTTTATGCCGAATTGCCTCGGTCCGGGGGTCTATACCGAACAGCCAACGTCACATATCGGGGCATCACCATAGGGAAGGTCACCGGCGTCGAACCAACCGAGCGGGGCGCGCGAGCAACCATGAGCATCGACAATGGCTACCAGATCCCCACCGACGCCTCGGCCAATGTGCACTCAGTGTCGGCGGTCGGCGAGCAGTTCGTTGACCTGGTGTCGACCCGCACCAGCGGTCCGTATCTGCGGCATGGGCAGACGATCACCACGACTACGGTCCCCAGCCAGATTGGCCCGGCGCTGGACGCCGCCAACCGTGGATTGGCAGTGCTGCCCAAAGACCGGGTCGCGTCGGTGCTGCACGAGGCGTCGGAGGCCGTGGGCGGGCTGGGATCCTCACTGAATCGCCTCATCGAAGCCACCCAGGCAATCGCCCACGATGTCAGGGGCAGCCTCGAGGACATCGACGACATCATCGAGCGTTCGGCGCCTATCATCGATAGCCAGGTCAATTCCGGCAACGAGATCGCCCGCTGGGCCGCCAACCTCAACACGCTGGCCGCTCAGACCGCGCAGACCGATCCGGCGGTGCGAAGCATTCTGGCCAACGCGGCACCGACTGCCGATCAGGTCAACGCCACGTTCAGCGACGTGCGGGAGTCGTTGCCGCAGACGCTGGCCAATCTCGAGGTCGTAATCGATATGCTCAAGCGCTACCACAACGGCGTCGAGCAGGCGTTGGTGTTCTTGCCGCAGTCCGGCGCGATCGCCCAGTCGGTTACTACAGAGTTCCCCGGCCAGGCCGGACTGGGTGTCGGCGGCCTGGCGCTCAACCAACCACCGCCGTGCCTGACCGGCTTCCTGCCGGCGTCGGAGTGGCGGTCACCTGCTGACACCAGCACCGCACCGCTACCCAAGGGCACCTACTGCAGGATTCCGATGGACGCGAGCAATGTGGTTCGTGGAGCACGCAACAACCCGTGTGTAGACGTGCCCGGCAAGCGGGCGGCGACCCCGCGGGAATGCCGCAGCAATGAAGCTTATGTGCCCGGGGGCACCAATCCCTGGTATGGGGACCCCAACCAGATGCTCAGCTGTCCCGCGCCGGCCGCGCGTTGTGACCAGCCGGTGAAGCCAGGCCAGGTGATCCCGGCGCCGTCAGTTAACAATGGCATCAACCCGCTGCCCGCCGATCAGCTGCCAGGCACACCTCCACCGGTCAACGATCCTTTGCAGCGACCTGGGTCAGGCACCGTCCAGTGCAATGGGCAACAACCCAACCCGTGCGTCTACACCCCGAGCACATTTCCTACAACCATTTACGACGTGCAGAGCGGCAAAGTCGTAGCACCCGACGGTGTGGTGTATTCCGTTGAGGCTTCGACTCATGCCGGAGCCGACGGATGGAAGGTGATGCTGGCACCAACCGGCTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

growth of symbiont in host organelle GO:0044121 biological_process
growth of symbiont in host GO:0044117 biological_process
extracellular region GO:0005576 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: O07784
GenBank: Rv0594
EnsemblBacteria: Rv0594
Mycobrowser: Rv0594

Summary

Name: Mce-family protein Mce2F
Family: Unknown
Protein Sequence: MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVGIGRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITTTTVPSQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWRSPADTSTAPLPKGTYCRIPMDASNVVRGARNNPCVDVPGKRAATPRECRSNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGINPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
Mass: 54,194 Da
Length: 516 Aa

Rv0594 doesn't seem to be a targeted by any drug.

ABC transporters mtu02010
mtu02010
Environmental Information Processing; Membrane transport

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.