rplL



Type
protein_coding
Name
rplL
Locus Name

Rv0652

Product

50S ribosomal protein L7/L12 RplL (SA1)

Functional Category

Information pathways

Location
748849..749241 (+ strand)
Gene Length
392 bp
Nucleotides
TGGCAAAGCTCTCCACCGACGAACTGCTGGACGCGTTCAAGGAAATGACCCTGTTGGAGCTCTCCGACTTCGTCAAGAAGTTCGAGGAGACCTTCGAGGTCACCGCCGCCGCTCCAGTCGCCGTCGCCGCCGCCGGTGCCGCCCCGGCCGGTGCCGCCGTCGAGGCTGCCGAGGAGCAGTCCGAGTTCGACGTGATCCTTGAGGCCGCCGGCGACAAGAAGATCGGCGTCATCAAGGTGGTCCGGGAGATCGTTTCCGGCCTGGGCCTCAAGGAGGCCAAGGACCTGGTCGACGGCGCGCCCAAGCCGCTGCTGGAGAAGGTCGCCAAGGAGGCCGCCGACGAGGCCAAGGCCAAGCTGGAGGCCGCCGGCGCCACCGTCACCGTCAAGTAG
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
Family

Bacterial ribosomal protein bL12 family

GO
InterPro

UniProt
P9WHE3
GenBank
Rv0652
EnsemblBacteria
Rv0652
Mycobrowser
Rv0652


Summary
Name
50S ribosomal protein L7/L12
Family
Bacterial ribosomal protein bL12 family
Protein Sequence
MAKLSTDELLDAFKEMTLLELSDFVKKFEETFEVTAAAPVAVAAAGAAPAGAAVEAAEEQSEFDVILEAAGDKKIGVIKVVREIVSGLGLKEAKDLVDGAPKPLLEKVAKEAADEAKAKLEAAGATVTVK
Mass
13,440 Da
Length
130 Aa

Rv0652 doesn't seem to be a targeted by any drug.


  • Ribosome

    Ribosome mtu03010

    mtu03010

    PATHWAY_MAP mtu03010 Ribosome


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.