Gene - combatTB X

Type: protein_coding
Name: Rv0691c
Locus Name: Rv0691c
Product: Probable transcriptional regulatory protein
Functional Category: Regulatory proteins
Location: 791070..791666 (- strand)
Gene Length: 596 bp
Nucleotides: ATGCCGCACGAGTCGCGGGTGGGCCGACGGCGCTCAACCACACCGCACCACATCAGCGATGTTGCCATCGAACTGTTCGCTGCCCACGGTTTCACCGATGTCAGCGTGGACGACATCGCCCGGGCGGCCGGCATCGCCCGCAGAACGTTGTTTCGCTACTACGCCTCCAAGAACGCCATCCCCTGGGGTGACTTCAGCACCCACCTTGCACAGCTACAAGGTCTACTCGACAATATCGATTCACGGATTCAGCTGAGGGACGCGTTGCGCGCAGCGCTGTTGGCCTTCAACACCTTTGACGAATCCGAAACCATCCGACACCGCAAGCGCATGCGGGTCATCTTGCAAACTCCTGAACTGCAGGCCTATTCGATGACCATGTATGCTGGCTGGCGCGAGGTGATCGCCAAATTCGTTGCCCGCAGATCGGGTGGAAAGACGACAGACTTTATGCCCCAAACCGTCGCCTGGACAATGCTGGGGGTCGCTCTGAGCGCCTATGAACATTGGCTGCGCGACGAATCCGTCTCCTTGACCGAAGCGCTCGGGGCCGCGTTTGACGTCGTCGGCGCCGGTCTGGACCGACTCAACCAGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

May regulate a gene cluster involved in mycofactocin expression. Mycofactocin is a conserved polypeptide that might serve as an electron carrier.

Family

Unknown

GO

InterPro

Summary

Name: Putative mycofactocin biosynthesis transcriptional regulator MftR
Family: Unknown
Protein Sequence: MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAGLDRLNQ
Mass: 22,264 Da
Length: 198 Aa

Rv0691c doesn't seem to be a targeted by any drug.

Rv0691c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.: BMC Genomics. 2011 Jan 11;12:21. doi: 10.1186/1471-2164-12-21.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.