Rv0696
- Type
- protein_coding
- Name
- Rv0696
- Locus Name
-
Rv0696
- Product
-
Probable membrane sugar transferase
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 795519..796931 (+ strand)
- Gene Length
- 1412 bp
- Nucleotides
-
TGACCGCGACCCGACTGCCTGACGGGTTCGCCGTCCAGGTTGACCGTCGCGTGCGAGTGCTTGGCGACGGCTCGGCCCTGCTCGGTGGCTCACCGACCCGGTTGCTGCGGCTGGCTCCCGCCGCACGAGGCCTGCTCTGTGACGGCCGCCTTAAGGTCCGCGACGAGGTCAGCGCGGAGCTGGCCCGCATCCTGCTGGACGCCACGGTGGCGCATCCACGGCCGCCGAGTGGGCCGTCACATCGTGACGTCACCGTCGTTATACCAGTACGGAACAACGCATCTGGTCTGCGGCGTCTGGTGACCTCGTTACGCGGATTACGCGTCATCGTGGTCGACGACGGTTCGGCGTGCCCGGTCGAGTCGGACGACTTTGTCGGCGCACATTGCGACATCGAAGTACTCCACCACCCCCACAGCAAGGGGCCGGCCGCGGCTCGCAACACCGGGCTAGCGGCCTGCACCACCGACTTCGTGGCGTTCCTGGATTCCGACGTGACGCCGCGGCGGGGATGGTTGGAATCCTTACTCGGCCACTTCTGCGATCCCACCGTCGCACTCGTCGCACCTCGCATCGTCAGCTTGGTGGAAGGCGAGAACCCGGTAGCTCGCTATGAGGCCCTGCACTCGTCGTTGGACCTTGGTCAGCGCGAAGCGCCGGTGTTACCGCATAGCACAGTCTCTTACGTGCCGAGCGCCGCCATCGTTTGCCGGAGTTCAGCCATCCGCGACGTCGGCGGCTTCGACGAGACCATGCACTCCGGGGAAGATGTCGACTTGTGCTGGCGGCTCATCGAGGCTGGTGCTCGGCTGCGCTACGAGCCAATTGCGCTGGTCGCCCATGACCATCGGACCCAATTGCGGGACTGGATCGCGCGCAAGGCGTTTTACGGCGGTTCGGCGGCTCCGCTAGCTGTGCGGCACCCGGACAAGACCGCGCCGCTGGTGATTTCGGGCGGGGCGCTGATGGCGTGGATCCTCATGTCGATCGGCACAGGCCTTGGTCGACTGGCGTCGTTGGTGATCGCGGTGCTGACTGGTCGCCGGATCGCCAGGGCCATGCGCTGCGCCGAGACGTCGTTCTTGGATGTGCTTGCCGTCGCCACCCGCGGGTTGTGGGCGGCCGCGCTGCAGCTGGCGTCGGCCATCTGCCGGCACTATTGGCCACTGGCATTGCTCGCGGCCATCCTGTCGCGCCGCTGTAGGCGGGTGGTGTTGATTGCGGCGGTAGTGGACGGTGTGGTGGATTGGCTTCGCCGCAGGGAGGGCGCCGACGATGATGCTGAACCGATTGGGCCGCTGACCTACCTAGTGCTGAAGCGCGTGGACGACTTGGCTTATGGCGCTGGCCTGTGGTACGGGGTGGTGCGCGAACGTAACATCGGCGCGCTCAAGCCGCAGATTCGTACCTAG
- Drug Resistance
- Mutations
- Function
- May play a role in the maturation of mycofactocin, a conserved polypeptide that might serve as an electron carrier. The genes for mycofactocin and other proteins proposed to function in its maturation are found in a conserved gene cluster.
- Family
-
Glycosyltransferase 2 family
- GO
-
- cytosol GO:0005829 cellular_component
- plasma membrane GO:0005886 cellular_component
- transferase activity GO:0016740 molecular_function
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- Putative mycofactocin biosynthesis glycosyltransferase MftF (EC 2.-.-.-)
- Family
- Glycosyltransferase 2 family
- Protein Sequence
-
MTATRLPDGFAVQVDRRVRVLGDGSALLGGSPTRLLRLAPAARGLLCDGRLKVRDEVSAELARILLDATVAHPRPPSGPSHRDVTVVIPVRNNASGLRRLVTSLRGLRVIVVDDGSACPVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACTTDFVAFLDSDVTPRRGWLESLLGHFCDPTVALVAPRIVSLVEGENPVARYEALHSSLDLGQREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLIEAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPLVISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVLAVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVVDWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALKPQIRT
- Mass
- 50,667 Da
- Length
- 470 Aa
Rv0696 doesn't seem to be a targeted by any drug.
Rv0696 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.
- BMC Genomics. 2011 Jan 11;12:21. doi: 10.1186/1471-2164-12-21.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.