Function

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). {ECO:0000255|HAMAP-Rule:MF_01331}.; FUNCTION: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01331}.

Family

Universal ribosomal protein uL22 family

GO

• cytosolic large ribosomal subunit GO:0022625 cellular_component
• structural constituent of ribosome GO:0003735 molecular_function
• large ribosomal subunit GO:0015934 cellular_component
• ribosome assembly GO:0042255 biological_process
• rRNA binding GO:0019843 molecular_function
• cell wall GO:0005618 cellular_component
• translation GO:0006412 biological_process

InterPro

• IPR001063
• IPR018260
• IPR036394
• IPR005727

UniProt

P9WHC1

GenBank

Rv0706

EnsemblBacteria

Rv0706

Mycobrowser

Rv0706

Rv0706 doesn't seem to be a targeted by any drug.

• 

  Ribosome mtu03010

  mtu03010

  PATHWAY_MAP mtu03010 Ribosome