rplX



Type
protein_coding
Name
rplX
Locus Name

Rv0715

Product

50S ribosomal protein L24 RplX

Functional Category

Information pathways

Location
811742..812059 (+ strand)
Gene Length
317 bp
Nucleotides
TGAAGGTCCACAAAGGCGACACCGTGCTGGTGATTTCGGGCAAAGATAAAGGGGCCAAGGGCAAAGTCTTGCAGGCGTATCCGGACCGCAACCGGGTATTGGTCGAGGGTGTCAACCGGATCAAGAAGCACACCGCGATCTCGACCACCCAGCGGGGCGCGCGTTCGGGTGGGATCGTCACCCAGGAAGCGCCGATCCATGTCTCCAACGTGATGGTGGTTGACTCCGACGGCAAGCCCACCCGAATCGGCTATCGGGTCGACGAGGAGACCGGCAAGCGCGTCCGTATCTCCAAGCGCAACGGCAAGGACATTTGA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. {ECO:0000255|HAMAP-Rule:MF_01326}.; FUNCTION: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. {ECO:0000255|HAMAP-Rule:MF_01326}.
Family

Universal ribosomal protein uL24 family

GO
InterPro

UniProt
P9WHB7
GenBank
Rv0715
EnsemblBacteria
Rv0715
Mycobrowser
Rv0715


5V7Q
Summary
Name
50S ribosomal protein L24
Family
Universal ribosomal protein uL24 family
Protein Sequence
MKVHKGDTVLVISGKDKGAKGKVLQAYPDRNRVLVEGVNRIKKHTAISTTQRGARSGGIVTQEAPIHVSNVMVVDSDGKPTRIGYRVDEETGKRVRISKRNGKDI
Mass
11,475 Da
Length
105 Aa

Rv0715 doesn't seem to be a targeted by any drug.


  • Ribosome

    Ribosome mtu03010

    mtu03010

    PATHWAY_MAP mtu03010 Ribosome


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.