rplR



Type
protein_coding
Name
rplR
Locus Name

Rv0720

Product

50S ribosomal protein L18 RplR

Functional Category

Information pathways

Location
813940..814308 (+ strand)
Gene Length
368 bp
Nucleotides
TGGCGCAATCAGTTTCCGCGACTCGACGAATCTCCCGCCTGCGCCGGCACACGCGGCTGCGGAAGAAGCTCTCGGGCACCGCGGAGCGCCCGCGGCTGGTGGTGCATCGGTCCGCGCGGCACATCCACGTGCAACTGGTGAACGACCTCAACGGCACCACCGTGGCCGCCGCTTCGTCGATCGAGGCCGATGTGCGCGGCGTGCCGGGTGACAAAAAGGCCCGCAGTGTGCGGGTCGGCCAGTTGATCGCCGAGCGGGCCAAAGCCGCCGGCATCGACACCGTGGTATTCGACCGCGGCGGGTATACCTACGGCGGACGAATCGCCGCGCTGGCCGACGCCGCACGCGAGAACGGATTGAGTTTCTGA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. {ECO:0000255|HAMAP-Rule:MF_01337}.
Family

Universal ribosomal protein uL18 family

GO
InterPro

UniProt
P9WHD1
GenBank
Rv0720
EnsemblBacteria
Rv0720
Mycobrowser
Rv0720


5V7Q
Summary
Name
50S ribosomal protein L18
Family
Universal ribosomal protein uL18 family
Protein Sequence
MAQSVSATRRISRLRRHTRLRKKLSGTAERPRLVVHRSARHIHVQLVNDLNGTTVAAASSIEADVRGVPGDKKARSVRVGQLIAERAKAAGIDTVVFDRGGYTYGGRIAALADAARENGLSF
Mass
13,184 Da
Length
122 Aa

Rv0720 doesn't seem to be a targeted by any drug.


  • Ribosome

    Ribosome mtu03010

    mtu03010

    PATHWAY_MAP mtu03010 Ribosome


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.