mmsB
- Type
- protein_coding
- Name
- mmsB
- Locus Name
-
Rv0751c
- Product
-
Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 842347..843231 (- strand)
- Gene Length
- 884 bp
- Nucleotides
-
ATGACGACCATCGCCTTCCTAGGTTTGGGCAACATGGGTGCGCCGATGTCGGCGAATCTGGTTGGTGCGGGCCACGTCGTGCGTGGATTCGACCCGGCACCCACGGCGGCGTCCGGCGCCGCCGCGCACGGTGTCGCGGTGTTTCGTAGCGCGCCCGAAGCGGTGGCCGAGGCCGACGTGGTCATCACCATGCTGCCCACCGGCGAGGTGGTCCGGCGCTGCTACACCGACGTGCTGGCCGCCGCGCGTCCGGCAACGCTGTTCATCGACAGCTCCACGATCTCGGTCACCGATGCCCGTGAGGTGCACGCGCTGGCCGAATCGCACGGCATGCTCCAACTGGATGCGCCGGTCTCCGGCGGGGTGAAGGGCGCCGCCGCCGCGACGCTGGCATTCATGGTCGGCGGCGACGAGTCCACGCTACGGCGGGCACGCCCGGTACTAGAGCCCATGGCGGGCAAGATCATTCACTGCGGCGCCGCCGGTGCCGGACAGGCCGCCAAGGTGTGCAACAACATGGTGCTGGCGGTGCAGCAGATCGCGATCGCCGAGGCGTTCGTGCTGGCCGAGAAGCTCGGGCTGTCCGCACAATCGTTGTTCGACGTCATCACCGGCGCGACCGGCAATTGCTGGGCGGTGCACACCAATTGCCCGGTGCCGGGCCCGGTGCCCACCTCACCGGCCAACAACGACTTCAAGCCCGGGTTTTCGACCGCGTTGATGAACAAGGACCTGGGCCTGGCGATGGATGCGGTGGCCGCCACCGGTGCGACGGCCCCGCTGGGCAGCCACGCCGCCGACATCTACGCCAAATTCGCCGCCGACCACGCCGACCTGGACTTCAGCGCGGTGATCCACACGTTGCGCGCGCGAGCAGACGCATA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
HIBADH-related family
- GO
-
- NADP binding GO:0050661 molecular_function
- 3-hydroxyisobutyrate dehydrogenase activity GO:0008442 molecular_function
- valine catabolic process GO:0006574 biological_process
- NAD binding GO:0051287 molecular_function
- InterPro
5Y8G
- Name
- Probable 3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31)
- Family
- HIBADH-related family
- Protein Sequence
-
MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDFSAVIHTLRARADA
- Mass
- 29,679 Da
- Length
- 294 Aa
Summary
Rv0751c doesn't seem to be a targeted by any drug.
-
-
Valine, leucine and isoleucine degradation mtu00280
mtu00280PATHWAY_MAP mtu00280 Valine, leucine and isoleucine degradation
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.