phoT
- Type
- protein_coding
- Name
- phoT
- Locus Name
-
Rv0820
- Product
-
Probable phosphate-transport ATP-binding protein ABC transporter PhoT
- Functional Category
-
Cell wall and cell processes
- Location
- 912726..913502 (+ strand)
- Gene Length
- 776 bp
- Nucleotides
-
TGGCCAAGCGGTTGGACCTCACGGACGTCAACATCTACTACGGGTCATTTCATGCGGTCGCTGATGTGTCGCTGGCGATTCTGCCCCGCAGCGTCACGGCGTTCATCGGTCCCTCGGGCTGCGGCAAGACGACGGTGCTGCGCACCTTGAACCGGATGCATGAGGTCATCCCCGGAGCTCGAGTCGAGGGTGCCGTACTGCTCGATGATCAAGATATCTACGCCCCCGGTATCGACCCGGTCGGTGTCCGCCGGGCAATCGGGATGGTGTTTCAGCGGCCGAATCCATTCCCCGCCATGTCGATTCGCAACAATGTGGTTGCCGGCCTGAAGCTGCAGGGTGTGCGCAATCGCAAGGTGCTCGACGATACGGCCGAATCCTCGCTGCGCGGCGCAAACCTGTGGGACGAGGTCAAGGATCGACTGGATAAACCCGGCGGCGGATTGTCTGGGGGGCAGCAGCAGCGGTTGTGCATCGCACGGGCAATCGCCGTGCAACCCGACGTGTTGCTGATGGACGAGCCCTGCTCCTCGCTGGACCCAATCTCCACCATGGCCATCGAAGACCTGATCAGCGAGCTCAAGCAGCAGTACACCATCGTCATCGTCACCCATAACATGCAGCAGGCTGCCCGGGTGAGTGATCAGACGGCATTCTTCAACCTGGAAGCGGTGGGAAAGCCGGGGCGGCTGGTAGAGATCGCCAGCACCGAGAAAATCTTCTCCAACCCGAACCAGAAGGCCACCGAGGACTACATCTCCGGGCGCTTCGGCTAG
- Drug Resistance
- Mutations
- Function
- Part of the ABC transporter complex PstSACB involved in phosphate import (Probable). Responsible for energy coupling to the transport system. {ECO:0000255|HAMAP-Rule:MF_01702, ECO:0000305|PubMed:20933472}.
- Family
-
ABC transporter superfamily, Phosphate importer (TC 3.A.1.7) family
- GO
-
- growth of symbiont in host GO:0044117 biological_process
- ATPase-coupled phosphate ion transmembrane transporter activity GO:0015415 molecular_function
- inorganic phosphate transmembrane transporter activity GO:0005315 molecular_function
- ATP binding GO:0005524 molecular_function
- plasma membrane GO:0005886 cellular_component
- InterPro
Summary
- Name
- Phosphate import ATP-binding protein PstB 1 (EC 7.3.2.1) (ABC phosphate transporter 1) (Phosphate-transporting ATPase 1)
- Family
- ABC transporter superfamily, Phosphate importer (TC 3.A.1.7) family
- Protein Sequence
-
MAKRLDLTDVNIYYGSFHAVADVSLAILPRSVTAFIGPSGCGKTTVLRTLNRMHEVIPGARVEGAVLLDDQDIYAPGIDPVGVRRAIGMVFQRPNPFPAMSIRNNVVAGLKLQGVRNRKVLDDTAESSLRGANLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSSLDPISTMAIEDLISELKQQYTIVIVTHNMQQAARVSDQTAFFNLEAVGKPGRLVEIASTEKIFSNPNQKATEDYISGRFG
- Mass
- 28,061 Da
- Length
- 258 Aa
Rv0820 doesn't seem to be a targeted by any drug.
-
-
ABC transporters mtu02010
mtu02010Environmental Information Processing; Membrane transport
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Effect of PstS sub-units or PknD deficiency on the survival of Mycobacterium tuberculosis.
- Tuberculosis (Edinb). 2010 Nov;90(6):338-45. doi: 10.1016/j.tube.2010.09.004. Epub 2010 Oct 8.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.