moaC2
- Type
- protein_coding
- Name
- moaC2
- Locus Name
-
Rv0864
- Product
-
Probable molybdenum cofactor biosynthesis protein C 2 MoaC2
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 962890..963393 (+ strand)
- Gene Length
- 503 bp
- Nucleotides
-
TGGCCAGGGCTTCTGGGGCATCCGACTACCGCTCGGGCGAGCTGTCGCACCAGGATGAGCGGGGGGCAGCGCACATGGTCGATATCACCGAGAAGGCAACCACGAAGCGAACAGCCGTTGCCGCGGGCATCTTACGTACCTCGGCGCAGGTGGTGGCGCTGATCTCGACTGGCGGGCTGCCCAAAGGGGATGCGCTGGCCACCGCGCGGGTGGCGGGCATTATGGCGGCCAAGCGCACCAGCGACCTGATCCCGCTGTGCCATCAACTCGCGCTTACCGGAGTCGACGTCGATTTCACCGTCGGCCAGTTGGATATCGAGATCACAGCGACGGTACGCAGTACCGACCGAACGGGCGTCGAGATGGAAGCGCTGACCGCTGTCAGCGTGGCCGCCCTCACGCTCTACGACATGATCAAGGCGGTCGATCCGGGCGCGCTTATCGATGACATCCGGGTGCTCCACAAAGAAGGCGGTCGTCGCGGGACCTGGACGAGGCGATGA
- Drug Resistance
- Mutations
- Function
- Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP). {ECO:0000255|HAMAP-Rule:MF_01224}.
- Family
-
MoaC family
- GO
-
- cyclic pyranopterin monophosphate synthase activity GO:0061799 molecular_function
- Mo-molybdopterin cofactor biosynthetic process GO:0006777 biological_process
- InterPro
4FDF
- Name
- Cyclic pyranopterin monophosphate synthase 2 (EC 4.6.1.17) (Molybdenum cofactor biosynthesis protein C 2)
- Family
- MoaC family
- Protein Sequence
-
MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
- Mass
- 17,598 Da
- Length
- 167 Aa
Summary
Rv0864 doesn't seem to be a targeted by any drug.
-
-
Folate biosynthesis mtu00790
mtu00790PATHWAY_MAP mtu00790 Folate biosynthesis
-
- Overexpression, purification, crystallization and preliminary X-ray analysis of putative molybdenum cofactor biosynthesis protein C (MoaC2) from Mycobacterium tuberculosis H37Rv.
- Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jun 1;68(Pt 6):687-91. doi: 10.1107/S174430911201665X. Epub 2012 May 23.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.