Gene - combatTB X

Rv0890c

Type: protein_coding
Name: Rv0890c
Locus Name: Rv0890c
Product: Probable transcriptional regulatory protein (probably LuxR-family)
Functional Category: Regulatory proteins
Location: 989948..992596 (- strand)
Gene Length: 2648 bp
Nucleotides: GTGCGGGCACTGTTGGCGCAGAACCGGCTCGTGACGCTATGCGGAACCGGCGGTGTCGGCAAGACCCGTCTGGCAATCCAGATCGCGAGTGCATCCGAACTTCGCGACGGTTTGTGCTTTGTCGATCTGGCCCCGATCACTGAATCCGGGATCGTCGCAGCCACGGCTGCGCGCGCCGTGGGTCTGCCCGATCAGCCGGGCCGTTCAACCATGGATAGTCTTCGCCGATTCATCGGCAATCGCCGCATGCTCATGGTGTTGGACAACTGTGAACATCTTCTCGATGCGTGCGCAGCGTTGGTCGTTGAGCTATTGGGGGCCTGTCCGGAGCTGACGATCTTAGCGACTAGCCGGGAGCCGATCGGGATGGCCGGCGAGATCACCTGGCGCGTACCGTCGATGTCGATAACCGACGAAGCAGTCGAATTGTTTGCTGACCGAGCCAGCCGAGTTCAGCCCGGGTTCACCATCGCCAATCACAACGCCGCGGCCGTCGGCGAGATCTGCCGGCGGCTAGACGGCATACCGCTGGCGATCGAGTTCGCTGCCGCACGGGTGCGGTCGATGTCACCGCTCGAGATTGCCGACGGTCTGGACGACTGTTTCCGGCTGTTGGCCGGCGGTGTGCGGGGCGCGGTGCAGCGCCAGCAGACACTTCGCGCCTCGATCGATTGGTCGCATGCACTGCTGACCGAGACCGAGCAAATCTTGTTTCGGCGACTGGCGCCATTTGTCGGCGGGTTCGACCTCGCCGCGGTGCGGGCGGTCGCCGCCGGTAGCGACCTGGATCCGTTTTCGGTGCTTGATCAGCTGACCCTGCTGGTAGACAAGTCGCTGGTGGTGGCCGACGACTGCCAGGGCCGCACGCGGTACCGGCTGCTGGAAACGGTGCGTCGGTACGCGCTGGAAAAACTGGGCGACTCCGGCGAGGCCGATGTGCACGCACGTCACCGTGACTACTACACGGCGCTGGCCGCCTCACTCAACACTCCTGCGGACAACGATCACCAACGGCTTGTCGCCCGGGCTGAGACCGAGATCGACAACCTGCGCGCCGCGTTCGCCTGGAGCCGGGAAAATGGCCATATCACCGAAGCGTTACAGCTCGCATCTTCGCTGCAACCAATCTGGTTCGGGCGGGCGCACCTGCGCGAGGGGTTGTCCTGGTTCAACTCGATCCTGGAAGACCAAAGGTTCCACCGGCTCGCTGTGTCAACAGCAGTACGGGCGCGAGCGCTCGCTGACAAGGCAATGCTCAGTACCTGGCTGGCCACCAGTCCGGTAGGCGCCACCGACATCATCGCTCCCGCACAACAAGCGCTGGCGATGGCACGTGAGGTGGGCGACCCCGCCGCGTTGGTGCGGGCGCTCACCGCCTGCGGCTGTAGCAGTGGCTACAACGCGGAGGCCGCTGCGCCCTATTTCGCCGAAGCGACCGACCTGGCACGCGCTATTGACGACAAATGGACGCTGTGTCAAATCCTCTACTGGCGGGGGGTGGGGACCTGCATATCAGGTGACCCGAATGCTTTGCGAGCCGCGGCAGAAGAATGCCGCGACCTGGCCGACACCATCGGCGACCGGTTCGTCTCACGTCACTGCAGCTTGTGGCTTAGTTTGGCGCAGATGTGGGCTGGCAATCTGACCGAAGCCCTCGAGCTATCCAGGGAAATCACTGCCGAGGCCGAGGCATCCAACGATGTGCCGACAAAGGTTCTCGGCCTATATACCCAAGCCCAGGTGCTGGCGTATTGCGGCGCCAGCGCGGCCCACGCCATAGCCGGGGCGTGCATTGCAGCCGCGACGGAGTTAGGCGGTGTGTACCAAGGCATTGGTTATGCGGCGATGACGTACGCCGCGCTGGCCGCCGGTGATGTCACGGCAGCGCTCGAGGCCAGCGACGCGGCGCGGCCGATTCTTAGGGCCCAGCCCGACCAGGTGACCATGCACCAGGTCCTGATGGCGCAGTTAGCCCTGGCAGGAGGTGATGCGATCGCCGCACGACAGTTCGCCAACGACGCCGTCGATGCGACCAATGGGTGGCACCGAATGGTGGCGTTGACAATACGCGCGCGCGTAGCCACCGCACGGGGCGAACCAGAACTGGCGCGCGATGATGCTCATGCTGCGCTGGCGTGCGGCGCCGAGCTGCACATCTACCAGGGCATGCCAGATGCCATGGAACTCCTCGCCGGCCTGGCCGGCGAGGTCGGCAGTCACTCCGAAGGTGTCCGCCTTCTCGGTGCCGCAGCCGCCCTTCGGCAACAGACACGTCAGGTCCGCTTCAAGATTTGGGATGCCGGCTACCAGGCCTCGGTGACGGCGCTTCGTGAGGCGATGGGTGATGAGGATTTCGACCGCGCCTGGGCCGAGGGGGCCGCCTTGTCCACCGACGAGGCGATCGCATATGCACAACGCGGTCGCGGTGAACGCAAGCGACCGGCCCGCGGGTGGGGCTCGTTGACCCCGACCGAACGCGACGTCGTGCGGTTGGTCAGCGAGGGGTTATCCAACAAGGACATTGCAAAACGGCTTTTCGTCTCGCCGCGCACTGTGCAAACCCACCTCACCCACGTCTACGCCAAACTTGGCTTGCCCTCCCGAGTACAACTGGTAGACGAGGCGGCACGCCGCGGCTCACCCTCGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

cell wall GO:0005618 cellular_component
cytosol GO:0005829 cellular_component
DNA binding GO:0003677 molecular_function
regulation of transcription, DNA-templated GO:0006355 biological_process

InterPro

UniProt: P9WMG1
GenBank: Rv0890c
EnsemblBacteria: Rv0890c
Mycobrowser: Rv0890c

Summary

Name: Putative HTH-type transcriptional regulator Rv0890c
Family: Unknown
Protein Sequence: MRALLAQNRLVTLCGTGGVGKTRLAIQIASASELRDGLCFVDLAPITESGIVAATAARAVGLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPELTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVRGAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRLLETVRRYALEKLGDSGEADVHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSREITAEAEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPELARDDAHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS
Mass: 94,496 Da
Length: 882 Aa

Rv0890c doesn't seem to be a targeted by any drug.

Rv0890c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Profiling of Mycobacterium tuberculosis gene expression during human macrophage infection: upregulation of the alternative sigma factor G, a group of transcriptional regulators, and proteins with unknown function.: Res Microbiol. 2006 Jun;157(5):445-55. doi: 10.1016/j.resmic.2005.10.007. Epub 2006 Jan 13.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.