Rv0901
- Type
- protein_coding
- Name
- Rv0901
- Locus Name
-
Rv0901
- Product
-
Possible conserved exported or membrane protein
- Functional Category
-
Cell wall and cell processes
- Location
- 1003957..1004484 (+ strand)
- Gene Length
- 527 bp
- Nucleotides
-
TGGAACACGTGCACTGGTGGCTGGCGGGCCTGGCGTTCACGCTCGGGATGGTGCTGACGTCGACGCTGATGGTCCGGCCCGTCGAACATCAAGTGCTGGTAAAGAAATCGGTCCGCGGGTCAAGCGCTAAGTCCAAGCCGCCAACGGCGAGAAAACCCGCCGTCAAGTCGGGCACCAAGAGAGAGGAGTCGCCGACGGCGAAGACCAAGGTGGCAACGGAGTCTGCTGCGGAGCAGATCCCGGTTGCCGGGGAGCCCGCGGCGGAGCCGATCCCGGTCGCCGGCGAGCCGGCGGCGCGTATTCCGGTGGTTCCGTACGCGCCGTACGGCCCGGGCTCGGCGCGCGCTGGTGCCGATGGCAGCGGACCGCAGGGGTGGCTGGTGAAGGGCCGCTCGGACACCAGGCTCTACTACACTCCCGAAGATCCGACGTACGACCCTACTGTCGCCCAGGTTTGGTTCCAGGACGAGGAGTCGGCAGCGCGGGCGTTTTTCACGCCGTGGCGCAAGAGCACACGGCGGACATGA
- Drug Resistance
- Mutations
- Function
- Required for wild-type expression of ArfA and ammonia secretion, not however part of an ammonia transporter. {ECO:0000269|PubMed:21410778}.
- Family
-
ArfC membrane protein family
- GO
-
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
-
- Unknown
Summary
- Name
- Uncharacterized membrane protein ArfC
- Family
- ArfC membrane protein family
- Protein Sequence
-
MEHVHWWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKSVRGSSAKSKPPTARKPAVKSGTKREESPTAKTKVATESAAEQIPVAGEPAAEPIPVAGEPAARIPVVPYAPYGPGSARAGADGSGPQGWLVKGRSDTRLYYTPEDPTYDPTVAQVWFQDEESAARAFFTPWRKSTRRT
- Mass
- 18,909 Da
- Length
- 175 Aa
Rv0901 doesn't seem to be a targeted by any drug.
Rv0901 doesn't seem to be involved in any pathway.
- Expression of the ompATb operon accelerates ammonia secretion and adaptation of Mycobacterium tuberculosis to acidic environments.
- Mol Microbiol. 2011 May;80(4):900-18. doi: 10.1111/j.1365-2958.2011.07619.x. Epub 2011 Mar 16.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.