Rv0944
- Type
- protein_coding
- Name
- Rv0944
- Locus Name
-
Rv0944
- Product
-
Possible formamidopyrimidine-DNA glycosylase (FAPY-DNA glycosylase)
- Functional Category
-
Information pathways
- Location
- 1053765..1054241 (+ strand)
- Gene Length
- 476 bp
- Nucleotides
-
TGGCCGGGACGCCGCAGCCGCGCGCGCTCGGGCCCGATGCGCTGGACGTCAGCACCGACGACCTGGCCGGGCTGTTGGCCGGCAACACCGGCCGGATCAAGACCGTCATCACCGACCAGAAGGTAATTGCCGGCATCGGCAACGCCTATAGTGACGAAATCCTGCACGTCGCGAAGATCTCGCCGTTCGCCACGGCCGGCAAGTTATCCGGCGCACAGCTCACCTGCCTGCATGAGGCGATGGCGTCGGTGCTGTCGGACGCGGTGCGCCGGTCCGTCGGCCAGGGCGCGGCCATGCTCAAAGGGGAGAAACGTTCTGGGCTTCGAGTACATGCGCGCACCGGGTTACCCTGCCCAGTGTGCGGTGACACCGTGCGGGAGGTGTCCTTCGCGGACAAGTCTTTTCAGTACTGTCCAACGTGTCAGACCGGTGGCAAGGCGCTGGCCGACCGGCGTATGTCGCGGCTGCTCAAGTAG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Unknown
- GO
-
- DNA-(apurinic or apyrimidinic site) endonuclease activity GO:0003906 molecular_function
- damaged DNA binding GO:0003684 molecular_function
- nucleotide-excision repair GO:0006289 biological_process
- zinc ion binding GO:0008270 molecular_function
- hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 molecular_function
- InterPro
Summary
- Name
- Uncharacterized formamidopyrimidine-DNA glycosylase-like protein
- Family
- Unknown
- Protein Sequence
-
MAGTPQPRALGPDALDVSTDDLAGLLAGNTGRIKTVITDQKVIAGIGNAYSDEILHVAKISPFATAGKLSGAQLTCLHEAMASVLSDAVRRSVGQGAAMLKGEKRSGLRVHARTGLPCPVCGDTVREVSFADKSFQYCPTCQTGGKALADRRMSRLLK
- Mass
- 16,495 Da
- Length
- 158 Aa
Rv0944 doesn't seem to be a targeted by any drug.
-
-
Base excision repair mtu03410
mtu03410Genetic Information Processing; Replication and repair
-
- Base excision and nucleotide excision repair pathways in mycobacteria.
- Tuberculosis (Edinb). 2011 Nov;91(6):533-43. doi: 10.1016/j.tube.2011.06.005. Epub 2011 Jul 18.
- The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts.
- DNA Repair (Amst). 2010 Feb 4;9(2):177-90. doi: 10.1016/j.dnarep.2009.11.008. Epub 2009 Dec 23.
- Novel DNA glycosylases from Mycobacterium tuberculosis.
- Biochemistry (Mosc). 2008 Apr;73(4):442-50.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.