esxI



Type
protein_coding
Name
esxI
Locus Name

Rv1037c

Product

Putative ESAT-6 like protein EsxI (ESAT-6 like protein 1)

Functional Category

Cell wall and cell processes

Location
1160544..1160828 (- strand)
Gene Length
284 bp
Nucleotides
ATGACCATCAACTATCAATTCGGGGACGTCGACGCTCACGGCGCCATGATCCGCGCTCAGGCCGGGTCGCTGGAGGCCGAGCATCAGGCCATCATTTCTGATGTGTTGACCGCGAGTGACTTTTGGGGCGGCGCCGGTTCGGCGGCCTGCCAGGGGTTCATTACCCAGCTGGGCCGTAACTTCCAGGTGATCTACGAGCAGGCCAACGCCCACGGGCAGAAGGTGCAGGCTGCCGGCAACAACATGGCACAAACCGACAGCGCCGTCGGCTCCAGCTGGGCCTA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Unknown
Family

WXG100 family, ESAT-6 subfamily

GO
InterPro

UniProt
P0DOA6
GenBank
Rv1037c
EnsemblBacteria
Rv1037c
Mycobrowser
Rv1037c


Summary
Name
ESAT-6-like protein EsxI (Antigen Mtb9.9B)
Family
WXG100 family, ESAT-6 subfamily
Protein Sequence
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
Mass
9,833 Da
Length
94 Aa

Rv1037c doesn't seem to be a targeted by any drug.


Rv1037c doesn't seem to be involved in any pathway.


Mycobacterium tuberculosis RNA Expression Patterns in Sputum Bacteria Indicate Secreted Esx Factors Contributing to Growth are Highly Expressed in Active Disease.
Front Microbiol. 2012 Jan 10;2:266. doi: 10.3389/fmicb.2011.00266. eCollection 2011.
Systematic genetic nomenclature for type VII secretion systems.
PLoS Pathog. 2009 Oct;5(10):e1000507. doi: 10.1371/journal.ppat.1000507. Epub 2009 Oct 30.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.
Expression cloning of an immunodominant family of Mycobacterium tuberculosis antigens using human CD4(+) T cells.
J Exp Med. 2000 Feb 7;191(3):551-60. doi: 10.1084/jem.191.3.551.