Gene - combatTB X

mmpL13b

Type: protein_coding
Name: mmpL13b
Locus Name: Rv1146
Product: Probable conserved transmembrane transport protein MmpL13b
Functional Category: Cell wall and cell processes
Location: 1273355..1274767 (+ strand)
Gene Length: 1412 bp
Nucleotides: TGGCTACCGTGGCATTCGTCGCGACCGCGTCGATCGTGATCACCCCGGCCGCGATTGTGTTGCTAGGTCCTCGGCTAGATGCGTTGGACGTGCGCCGACTGGTGCGTCGGCTGCTGGGCCGGCCCGATCCGGTGCACAAACCGGTCAAGCAACTGTTCTGGTACCGGTCGAGCAAGTTCGTGATGCGCCGTTGGCTGCCGGTCGGTACGGCTGTTGTCGCGCTGCTGGTGCTGCTCGGGCTGCCGTTCTTGTCGGTGAAGTGGGGTTTCCCGGACGACCGGGTGTTGCCGCGGTCGGCGTCGGCCCGTCAAGTCGGCGATATCTTGCGCGATGACTTTGGCCACGATCCTGCGACGCAGATACCCATCGTCGTCCCGGACGCTCGTGGTCTCGGCCCGGTCGAACTTGACAGCTACGCAGCCGAGTTGTCCCGGGTGCCCGACGTATCCGCGGTAGCCGCCCCGACGGGCACGTTCGTAGACGGCAGCTGGGTGGGAACGCCGCGCGGGGCCACCGGGTTGGCTGAGGGCAGCGCGTTCCTGACGGTGAGCAGCACGGCGCCGCTGTTTTCGCGAGCCTCCGATATCCAGCTCAAGCGGTTGCACCAGGTGGCAGGGCCGGCCGGTCGATCCGTCGTGATGGCCGGTGTCGCGCAGGTCAACCGCGACAGTGTCGACGCGGTGACCGATCGGCTTCCGATGGTGCTAGGGCTAATTGCCGCGATCACCTACGTACTGTTGTTCCTGCTCACCGGCAGCGTGGTGCTGCCGGCGAAAGCGTTGGTTTGTAATGTGTTATCGCTGACCGCGGCGTTTGGCGCGTTGGTGTGGATCTTCCAGGAAGGCCATTTCGGTGCCCTGGGAACGACTCCGAGCGGGACGTTGGTGGCGAATATGCCGGTCCTACTGTTTTGCATCGCATTCGGTTTGTCCATGGACTACGAGGTGTTTCTGGTCTCCAGGATTCGGGAGTACTGGTTGGAATCCGGAGCCGCGCGACCCGCGCGAAGAAGCGTCGCAGAGGTGCACGCCGCCAACGACGAGAGCGTCGCGCTCGGCGTGGCCCGCACCGGTCGGGTGATCACCGCGGCAGCGTTGGTGATGTCCATGTCGTTCGCCGCGTTGATCGCTGCGCACGTGTCGTTCATGCGGATGTTCGGCCTCGGCCTGACTTTAGCCGTGGCTGCAGACGCCACACTGGTGCGGATGGTCGTGGTCCCAGCATTCATGCATGTGACGGGCCGCTGGAATTGGTGGGCACCGAGACCCCTGGCGTGGCTGCATGAGCGGTTCGGTGTCAGCGAGGCAGCAGAGCCGGTTTCGAGGAGACGTTCCCACGCCGGTGGGTTGGGCAAGATTGCCGGACGAAGCGACGGTCAGACGATCCCTGCCTCGCTGACGCGCAATGGTTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

positive regulation by symbiont of host immune response GO:0052556 biological_process
integral component of membrane GO:0016021 cellular_component

InterPro

IPR004869

UniProt: O06546
GenBank: Rv1146
EnsemblBacteria: Rv1146
Mycobrowser: Rv1146

Summary

Name: Probable conserved transmembrane transport protein MmpL13b
Family: Unknown
Protein Sequence: MATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG
Mass: 50,059 Da
Length: 470 Aa

Rv1146 doesn't seem to be a targeted by any drug.

Rv1146 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.