mrp
- Type
- protein_coding
- Name
- mrp
- Locus Name
-
Rv1229c
- Product
-
Probable Mrp-related protein Mrp
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1371777..1372949 (- strand)
- Gene Length
- 1172 bp
- Nucleotides
-
ATGCCAAGCCGCCTACACTCGGCGGTGATGTCCGGAACTCGTGATGGCGACCTGAACGCGGCGATACGCACCGCGCTGGGCAAGGTAATCGACCCCGAATTGCGGCGCCCCATCACCGAACTGGGGATGGTCAAAAGCATCGACACCGGCCCGGATGGGAGCGTGCACGTCGAGATCTACCTGACCATCGCCGGCTGCCCGAAGAAGTCCGAAATCACCGAGCGTGTCACCCGGGCGGTCGCCGACGTGCCAGGCACTTCGGCGGTGCGGGTCAGCTTGGACGTGATGAGCGACGAGCAGCGCACCGAGCTGCGTAAGCAGTTGCGTGGCGATACCCGCGAACCCGTCATCCCGTTCGCGCAACCCGATTCCTTGACCCGGGTGTATGCCGTGGCTTCCGGTAAGGGCGGAGTCGGAAAGTCCACCGTCACGGTCAACCTGGCCGCCGCGATGGCCGTCCGCGGCCTGTCGATCGGGGTGCTGGACGCTGATATCCACGGCCACTCTATCCCCCGGATGATGGGCACCACCGACCGGCCTACCCAGGTTGAGTCGATGATCCTGCCGCCGATCGCCCACCAGGTGAAGGTCATCTCGATAGCCCAGTTCACCCAGGGCAACACCCCGGTGGTGTGGCGCGGGCCGATGCTGCACCGGGCGTTGCAGCAGTTTCTGGCCGACGTGTACTGGGGGGATCTGGACGTGCTGCTGCTGGACTTGCCGCCCGGAACCGGCGACGTCGCCATCTCGGTGGCTCAACTGATCCCCAACGCCGAACTCCTGGTGGTCACCACCCCGCAGCTGGCCGCCGCGGAGGTGGCCGAACGGGCCGGCAGCATCGCGCTGCAAACCCGCCAACGCATCGTCGGCGTCGTGGAGAACATGTCGGGGCTCACGCTGCCGGACGGCACCACGATGCAGGTGTTCGGCGAGGGCGGTGGCCGGCTGGTCGCCGAGCGGTTGTCGCGTGCGGTCGGCGCCGACGTGCCGCTGCTGGGTCAGATCCCGCTGGACCCCGCACTGGTGGCCGCCGGCGATTCGGGCGTACCGCTCGTGTTGAGCTCGCCGGACTCGGCGATCGGCAAGGAACTGCATAGCATCGCCGACGGCTTGTCGACTCGACGACGCGGATTGGCGGGCATGTCGCTGGGGTTGGACCCGACACGACGCTA
- Drug Resistance
- Mutations
- Function
- Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP. {ECO:0000255|HAMAP-Rule:MF_02040}.
- Family
-
MIP18 family; Mrp/NBP35 ATP-binding proteins family
- GO
-
- metal ion binding GO:0046872 molecular_function
- ATP binding GO:0005524 molecular_function
- 4 iron, 4 sulfur cluster binding GO:0051539 molecular_function
- ATPase activity GO:0016887 molecular_function
- iron-sulfur cluster assembly GO:0016226 biological_process
- InterPro
Summary
- Name
- Iron-sulfur cluster carrier protein
- Family
- MIP18 family; Mrp/NBP35 ATP-binding proteins family
- Protein Sequence
-
MSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTGPDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQRTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAAMAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISIAQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAISVAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTLPDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVPLVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR
- Mass
- 40,084 Da
- Length
- 381 Aa
Rv1229c doesn't seem to be a targeted by any drug.
Rv1229c doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.