Gene - combatTB X

Type: protein_coding
Name: oppB
Locus Name: Rv1283c
Product: Probable oligopeptide-transport integral membrane protein ABC transporter OppB
Functional Category: Cell wall and cell processes
Location: 1436140..1437117 (- strand)
Gene Length: 977 bp
Nucleotides: ATGACGCGCTATCTGGCCCGCCGGTTGCTCAACTACCTGGTGCTGCTGGCGCTGGCGTCGTTTTTGACGTACTGCCTGACCTCGCTGGCGTTCTCGCCGCTGGAAAGCCTGATGCAACGCAGTCCGCGCCCACCGCAAGCGGTTATCGATGCCAAGGCACACGATCTCGGCTTGGACAGACCCATACTGGCCCGCTACGCCAACTGGGTATCGCATGCCGTCCGTGGCGACTTCGGAACCACCATCACCGGCCAGCCTGTCGGTACCGAACTGGGGCGCCGGATCGGAGTCAGCCTGCGGCTGCTGGTCGTTGGATCGGTATTCGGCACGGTGGCCGGTGTGGTGATCGGGGCGTGGGGTGCCATCCGGCAGTACCGGCTCAGCGACCGCGTCATGACCACGCTGGCGCTGCTGGTGTTGAGCACACCGACGTTTGTGGTGGCCAACCTGTTGATCCTGGGCGCCCTGCGGGTCAACTGGGCAGTGGGCATCCAGCTTTTCGACTACACCGGGGAGACGTCACCCGGCGTTGCCGGCGGGGTGTGGGATCGGCTAGGCGACCGGTTGCAGCATTTGATCCTGCCATCGCTGACGTTGGCGCTGGCGGCCGCCGCCGGGTTCAGCCGCTACCAGCGCAACGCGATGCTGGATGTCCTCGGCCAGGATTTCATTCGCACCGCCCGCGCCAAGGGGCTGACCCGACGACGGGCCCTACTCAAGCATGGCCTGCGAACGGCGCTAATACCGATGGCCACGCTGTTCGCCTACGGGGTGGCCGGGTTGGTCACCGGAGCGGTTTTCGTCGAGAAGATCTTCGGCTGGCACGGCATGGGTGAATGGATGGTCCGCGGTATCTCGACTCAGGACACCAACATCGTCGCGGCAATTACCGTGTTCTCCGGCGCGGTCGTGTTGCTGGCCGGTTTGCTCTCGGACGTGATCTACGCGGCTTTGGACCCGAGGGTACGGGTGTCATG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Binding-protein-dependent transport system permease family, OppBC subfamily

GO

transmembrane transport GO:0055085 biological_process
protein transport GO:0015031 biological_process
plasma membrane GO:0005886 cellular_component
evasion or tolerance by symbiont of host-produced nitric oxide GO:0052060 biological_process
integral component of membrane GO:0016021 cellular_component

InterPro

Summary

Name: Putative peptide transport permease protein Rv1283c
Family: Binding-protein-dependent transport system permease family, OppBC subfamily
Protein Sequence: MTRYLARRLLNYLVLLALASFLTYCLTSLAFSPLESLMQRSPRPPQAVIDAKAHDLGLDRPILARYANWVSHAVRGDFGTTITGQPVGTELGRRIGVSLRLLVVGSVFGTVAGVVIGAWGAIRQYRLSDRVMTTLALLVLSTPTFVVANLLILGALRVNWAVGIQLFDYTGETSPGVAGGVWDRLGDRLQHLILPSLTLALAAAAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRRALLKHGLRTALIPMATLFAYGVAGLVTGAVFVEKIFGWHGMGEWMVRGISTQDTNIVAAITVFSGAVVLLAGLLSDVIYAALDPRVRVS
Mass: 35,083 Da
Length: 325 Aa

Rv1283c doesn't seem to be a targeted by any drug.

Quorum sensing mtu02024
mtu02024
Cellular Processes; Cellular community - prokaryotes

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.