Function

Involved in the biosynthesis of the disaccharide D-N-acetylglucosamine-L-rhamnose which plays an important role in the mycobacterial cell wall as a linker connecting arabinogalactan and peptidoglycan via a phosphodiester linkage. Catalyzes the transfer of the N-acetylglucosamine-1-phosphate (GlcNAc-1P) moiety from UDP-GlcNAc onto the carrier lipid decaprenyl phosphate (C50-P), yielding GlcNAc-pyrophosphoryl-decaprenyl (GlcNAc-PP-C50). {ECO:0000269|PubMed:20637039}.

Family

Glycosyltransferase 4 family, WecA subfamily

GO

• cell wall organization GO:0071555 biological_process
• cell wall macromolecule biosynthetic process GO:0044038 biological_process
• lipopolysaccharide biosynthetic process GO:0009103 biological_process
• magnesium ion binding GO:0000287 molecular_function
• manganese ion binding GO:0030145 molecular_function
• integral component of plasma membrane GO:0005887 cellular_component
• phospho-N-acetylmuramoyl-pentapeptide-transferase activity GO:0008963 molecular_function
• plasma membrane GO:0005886 cellular_component
• capsule polysaccharide biosynthetic process GO:0045227 biological_process
• phosphotransferase activity, for other substituted phosphate groups GO:0016780 molecular_function
• transferase activity, transferring glycosyl groups GO:0016757 molecular_function

InterPro

• IPR000715

UniProt

P9WMW5

GenBank

Rv1302

EnsemblBacteria

Rv1302

Mycobrowser

Rv1302

Rv1302 doesn't seem to be a targeted by any drug.

• 

  Arabinogalactan biosynthesis - Mycobacterium mtu00572

  mtu00572

  Metabolism; Glycan biosynthesis and metabolism