atpH
- Type
- protein_coding
- Name
- atpH
- Locus Name
-
Rv1307
- Product
-
Probable ATP synthase delta chain AtpH
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1461843..1463183 (+ strand)
- Gene Length
- 1340 bp
- Nucleotides
-
TGTCGACGTTTATCGGACAGCTGTTCGGGTTCGCGGTCATCGTTTATCTGGTGTGGCGATTTATCGTGCCGCTCGTAGGGCGTTTGATGTCCGCACGGCAGGACACGGTGCGCCAACAGCTGGCGGATGCGGCGGCGGCCGCCGACCGGCTGGCGGAGGCGAGTCAAGCTCACACGAAGGCGCTGGAAGACGCCAAGTCGGAAGCGCACCGTGTTGTGGAAGAGGCCAGGACAGATGCCGAACGCATCGCAGAACAACTAGAGGCCCAGGCCGACGTCGAGGCGGAGCGCATCAAAATGCAGGGTGCCCGTCAGGTCGACCTCATCCGGGCACAGCTGACCCGTCAGCTTCGCCTCGAGCTCGGTCACGAATCGGTGCGCCAGGCAAGGGAATTGGTACGCAATCACGTGGCCGATCAGGCACAACAATCGGCCACCGTCGACCGCTTCCTGGATCAGCTCGATGCGATGGCGCCGGCTACGGCCGATGTCGATTACCCACTGCTGGCCAAGATGCGCTCAGCCAGCCGGAGGGCATTAACCAGCCTGGTGGATTGGTTCGGCACCATGGCCCAGGACCTCGACCATCAAGGTCTGACCACCCTCGCCGGCGAGCTGGTGTCGGTAGCAAGACTGCTGGACCGCGAGGCCGTCGTCACCCGCTATCTCACCGTGCCAGCCGAAGATGCGACGCCCAGGATCCGGCTGATCGAACGGCTGGTGTCCGGCAAGGTCGGCGCGCCAACGCTCGAGGTGTTGCGCACAGCCGTATCGAAGCGCTGGTCGGCCAATTCCGATTTGATCGATGCGATCGAACACGTGTCGCGGCAGGCGCTGTTAGAACTCGCCGAACGTGCGGGTCAGGTCGACGAGGTGGAAGACCAGTTATTCCGGTTTTCCCGCATTCTCGACGTGCAGCCCCGGCTTGCCATCCTGTTGGGTGACTGTGCCGTTCCGGCCGAAGGCCGAGTCCGGTTGCTGCGCAAGGTGCTTGAGCGTGCCGACAGTACCGTCAACCCGGTCGTGGTCGCGCTGTTGTCTCACACCGTCGAGCTGCTGCGGGGTCAGGCAGTTGAGGAAGCGGTGCTGTTCCTGGCCGAAGTTGCGGTGGCTCGCCGCGGCGAAATCGTCGCGCAGGTCGGCGCGGCGGCCGAGCTCAGCGATGCTCAGCGCACTCGCCTCACCGAAGTGCTGAGCCGTATCTACGGTCACCCCGTGACCGTGCAGCTGCATATCGACGCCGCGCTGCTGGGCGGATTGTCCATCGCGGTCGGTGACGAAGTGATCGACGGTACGCTCTCGTCTCGTCTAGCTGCGGCCGAGGCACGACTGCCCGACTGA
- Drug Resistance
- Mutations
- Function
- F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). {ECO:0000250}.; FUNCTION: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral "stator" stalk which links F(1) to F(0) (By similarity). {ECO:0000250}.
- Family
-
ATPase B chain family; ATPase delta chain family
- GO
-
- proton-transporting ATP synthase activity, rotational mechanism GO:0046933 molecular_function
- ATP synthesis coupled proton transport GO:0015986 biological_process
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 cellular_component
- proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- ATP synthase subunit b-delta [Includes: ATP synthase subunit b (ATP synthase F(0) sector subunit b 2) (ATPase subunit I 2) (F-type ATPase subunit b 2) (F-ATPase subunit b 2); ATP synthase subunit delta (ATP synthase F(1) sector subunit delta) (F-type ATPase subunit delta) (F-ATPase subunit delta)]
- Family
- ATPase B chain family; ATPase delta chain family
- Protein Sequence
-
MSTFIGQLFGFAVIVYLVWRFIVPLVGRLMSARQDTVRQQLADAAAAADRLAEASQAHTKALEDAKSEAHRVVEEARTDAERIAEQLEAQADVEAERIKMQGARQVDLIRAQLTRQLRLELGHESVRQARELVRNHVADQAQQSATVDRFLDQLDAMAPATADVDYPLLAKMRSASRRALTSLVDWFGTMAQDLDHQGLTTLAGELVSVARLLDREAVVTRYLTVPAEDATPRIRLIERLVSGKVGAPTLEVLRTAVSKRWSANSDLIDAIEHVSRQALLELAERAGQVDEVEDQLFRFSRILDVQPRLAILLGDCAVPAEGRVRLLRKVLERADSTVNPVVVALLSHTVELLRGQAVEEAVLFLAEVAVARRGEIVAQVGAAAELSDAQRTRLTEVLSRIYGHPVTVQLHIDAALLGGLSIAVGDEVIDGTLSSRLAAAEARLPD
- Mass
- 48,806 Da
- Length
- 446 Aa
Rv1307 doesn't seem to be a targeted by any drug.
-
-
Oxidative phosphorylation mtu00190
mtu00190PATHWAY_MAP mtu00190 Oxidative phosphorylation
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.