atpD
- Type
- protein_coding
- Name
- atpD
- Locus Name
-
Rv1310
- Product
-
Probable ATP synthase beta chain AtpD
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1465841..1467301 (+ strand)
- Gene Length
- 1460 bp
- Nucleotides
-
TGACTACCACTGCCGAAAAGACCGACCGGCCGGGAAAGCCGGGAAGCTCCGACACCAGCGGCCGCGTGGTACGGGTCACTGGGCCCGTCGTCGACGTCGAGTTTCCTCGCGGTTCCATCCCCGAGCTGTTCAATGCACTGCACGCTGAGATCACCTTCGAGTCGCTGGCGAAAACCCTCACCTTGGAGGTGGCGCAGCACCTCGGCGACAACCTGGTGCGCACCATCTCGCTGCAGCCGACCGACGGCTTGGTGCGCGGCGTCGAGGTGATCGACACCGGGAGGTCGATCTCGGTGCCGGTCGGTGAGGGTGTGAAGGGCCACGTCTTCAATGCGCTGGGAGATTGCCTGGACGAGCCGGGATATGGCGAAAAATTCGAACACTGGTCGATTCACCGCAAGCCGCCGGCGTTCGAGGAGCTGGAGCCTCGGACCGAGATGCTCGAGACCGGTCTGAAGGTGGTCGACCTGCTGACTCCGTATGTTCGTGGCGGCAAGATCGCACTGTTCGGCGGTGCCGGGGTGGGCAAGACGGTGCTGATTCAGGAGATGATCAACCGCATCGCCCGTAACTTCGGTGGTACGTCGGTGTTCGCCGGAGTGGGCGAGCGCACCCGCGAGGGCAACGATCTGTGGGTCGAGCTTGCCGAAGCCAACGTGCTCAAGGACACCGCGCTGGTATTCGGACAGATGGACGAGCCGCCGGGCACCCGTATGCGTGTTGCGCTGTCTGCGCTGACGATGGCGGAGTGGTTCCGTGACGAGCAGGGTCAAGACGTATTGCTGTTCATCGACAACATCTTCCGGTTCACCCAGGCTGGGTCGGAAGTGTCGACGCTTCTCGGCCGGATGCCGTCGGCCGTGGGATACCAGCCCACGCTGGCCGACGAGATGGGCGAGCTGCAGGAGCGCATCACCTCGACGCGGGGACGCTCGATCACGTCGATGCAAGCCGTCTACGTGCCCGCCGACGACTACACCGACCCAGCGCCGGCGACCACGTTCGCCCACCTGGACGCCACGACCGAGCTATCCCGTGCGGTGTTCTCCAAGGGCATCTTCCCCGCCGTGGACCCGCTGGCGTCCAGCTCGACCATCCTGGACCCCAGCGTTGTCGGGGATGAGCACTACCGCGTGGCCCAGGAAGTCATCCGGATCCTGCAGCGTTACAAGGACCTTCAGGACATTATCGCGATCCTCGGTATCGACGAGTTGTCGGAGGAGGACAAGCAGCTGGTGAACCGCGCCCGGCGTATCGAGCGGTTCCTATCGCAGAACATGATGGCAGCCGAACAGTTCACCGGCCAGCCGGGTTCGACCGTCCCGGTGAAGGAGACCATTGAAGCGTTCGACCGCTTGTGCAAGGGCGATTTCGATCACGTACCCGAACAGGCCTTCTTCTTGATCGGTGGCCTTGATGACCTGGCCAAGAAAGCCGAGAGTCTCGGCGCCAAGCTGTGA
- Drug Resistance
- Mutations
- Function
- Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. {ECO:0000255|HAMAP-Rule:MF_01347}.
- Family
-
ATPase alpha/beta chains family
- GO
-
- proton-transporting ATP synthase activity, rotational mechanism GO:0046933 molecular_function
- ATP synthesis coupled proton transport GO:0015986 biological_process
- cell wall GO:0005618 cellular_component
- extracellular region GO:0005576 cellular_component
- ATP binding GO:0005524 molecular_function
- cytosol GO:0005829 cellular_component
- plasma membrane GO:0005886 cellular_component
- proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 cellular_component
- InterPro
Summary
- Name
- ATP synthase subunit beta (EC 7.1.2.2) (ATP synthase F1 sector subunit beta) (F-ATPase subunit beta)
- Family
- ATPase alpha/beta chains family
- Protein Sequence
-
MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAESLGAKL
- Mass
- 53,094 Da
- Length
- 486 Aa
Rv1310 doesn't seem to be a targeted by any drug.
-
-
Oxidative phosphorylation mtu00190
mtu00190PATHWAY_MAP mtu00190 Oxidative phosphorylation
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.