pyrR
- Type
- protein_coding
- Name
- pyrR
- Locus Name
-
Rv1379
- Product
-
Probable pyrimidine operon regulatory protein PyrR
- Functional Category
-
Regulatory proteins
- Location
- 1552654..1553235 (+ strand)
- Gene Length
- 581 bp
- Nucleotides
-
TGGGTGCTGCGGGTGATGCCGCAATCGGCCGGGAGTCCCGCGAGTTGATGTCCGCGGCCGACGTCGGCCGCACGATTTCGCGCATCGCGCATCAGATTATCGAGAAGACCGCGTTAGATGACCCAGTCGGACCCGACGCGCCGCGGGTGGTGCTGCTGGGAATCCCGACCCGTGGCGTGACGCTGGCGAATCGCCTGGCCGGCAATATCACCGAATACAGCGGCATCCACGTCGGCCATGGCGCGCTGGACATCACCCTGTACCGCGACGATCTGATGATCAAGCCGCCGCGGCCCTTGGCGTCGACGTCGATCCCGGCCGGTGGGATCGATGACGCGCTGGTGATCCTGGTCGATGACGTGCTCTACTCCGGGCGCTCGGTGCGTTCCGCCCTGGACGCGCTGCGCGACGTGGGCCGGCCGCGGGCGGTGCAATTGGCGGTGCTGGTCGACAGGGGTCACCGGGAACTGCCGCTGCGCGCCGACTATGTGGGCAAGAACGTTCCGACCTCGCGCAGCGAGAGCGTGCACGTGCGGCTGCGCGAGCACGACGGCCGTGACGGCGTGGTGATCTCGCGATGA
- Drug Resistance
- Mutations
- Function
- Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. {ECO:0000255|HAMAP-Rule:MF_01219}.; FUNCTION: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. {ECO:0000255|HAMAP-Rule:MF_01219}.
- Family
-
Purine/pyrimidine phosphoribosyltransferase family, PyrR subfamily
- GO
-
- nucleoside metabolic process GO:0009116 biological_process
- cell wall GO:0005618 cellular_component
- regulation of transcription, DNA-templated GO:0006355 biological_process
- uracil phosphoribosyltransferase activity GO:0004845 molecular_function
- InterPro
1W30
- Name
- Bifunctional protein PyrR [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9)]
- Family
- Purine/pyrimidine phosphoribosyltransferase family, PyrR subfamily
- Protein Sequence
-
MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRVVLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPLASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR
- Mass
- 20,627 Da
- Length
- 193 Aa
Summary
Rv1379 doesn't seem to be a targeted by any drug.
Rv1379 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.