carB
- Type
- protein_coding
- Name
- carB
- Locus Name
-
Rv1384
- Product
-
Probable carbamoyl-phosphate synthase large chain CarB (carbamoyl-phosphate synthetase ammonia chain)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1557101..1560448 (+ strand)
- Gene Length
- 3347 bp
- Nucleotides
-
TGCCCCGTCGCACCGATCTGCACCACGTGCTGGTCATCGGCTCCGGGCCGATCGTCATCGGCCAGGCGTGCGAGTTCGACTACTCCGGGACTCAGGCGTGCCGGGTGCTGCGCGCCGAGGGCTTGCAGGTCAGCCTGGTGAACTCTAATCCGGCCACCATCATGACCGACCCGGAGTTCGCCGACCACACCTACGTAGAGCCCATCACCCCGGCGTTCGTGGAGCGGGTTATCGCCCAACAGGCCGAGCGGGGCAACAAGATCGACGCCCTGCTGGCGACCCTGGGTGGGCAGACCGCGCTGAACACCGCGGTCGCGCTGTACGAGAGCGGGGTGCTGGAAAAGTACGGCGTGGAACTCATCGGCGCCGATTTCGACGCCATCCAGCGCGGCGAGGACCGGCAGCGGTTCAAGGACATCGTCGCCAAGGCCGGTGGCGAATCCGCCCGGAGCCGAGTGTGTTTCACCATGGCCGAAGTGCGTGAGACGGTCGCCGAGCTCGGCCTGCCGGTGGTGGTGCGGCCGAGCTTCACCATGGGCGGGCTGGGTTCGGGGATAGCGTACTCCACCGACGAGGTCGACCGGATGGCCGGCGCCGGGCTGGCGGCCTCGCCCAGCGCCAACGTGCTCATCGAGGAATCGATTTACGGCTGGAAGGAATTCGAACTCGAGCTGATGCGCGACGGCCACGACAACGTGGTGGTGGTGTGCTCGATCGAAAACGTCGACCCGATGGGTGTGCACACCGGCGACTCGGTCACCGTCGCGCCGGCGATGACGTTGACCGACCGGGAATACCAGCGGATGCGCGACCTGGGCATCGCGATCCTGCGCGAGGTGGGTGTGGACACCGGCGGCTGCAACATCCAGTTCGCGGTCAACCCGCGCGACGGTCGGCTGATCGTCATCGAGATGAACCCGCGGGTGTCGCGTTCCAGTGCGTTGGCGTCCAAGGCGACCGGCTTTCCGATCGCCAAGATCGCCGCCAAACTGGCCATCGGTTACACCCTCGACGAGATCGTCAACGACATCACAGGGGAAACGCCGGCCTGTTTCGAACCCACCCTGGACTACGTGGTGGTCAAGGCGCCGCGGTTCGCGTTCGAGAAGTTCCCCGGTGCCGATCCCACCCTGACCACCACCATGAAATCTGTCGGTGAGGCAATGTCGTTGGGCCGCAACTTCGTCGAGGCGCTCGGCAAGGTGATGCGCTCGCTGGAGACGACCCGCGCCGGGTTCTGGACGGCACCGGATCCCGACGGCGGCATCGAGGAAGCCCTGACCCGGCTGCGGACCCCGGCCGAAGGCCGGCTCTACGACATCGAGCTGGCGTTGCGGCTGGGTGCGACGGTGGAACGGGTGGCCGAGGCCAGCGGTGTCGACCCGTGGTTCATCGCGCAGATCAACGAGCTGGTCAATCTGCGCAACGAACTCGTCGCGGCACCCGTGCTGAACGCCGAGCTGCTGCGGCGCGCCAAGCACAGCGGACTATCGGATCACCAGATCGCGTCGCTGAGACCGGAATTGGCCGGCGAGGCCGGCGTGCGGTCACTGCGCGTGCGCCTGGGCATCCACCCGGTATACAAGACGGTGGACACCTGCGCGGCGGAGTTCGAAGCCCAAACCCCCTACCACTACAGCAGCTACGAGCTCGACCCCGCCGCCGAAACAGAGGTGGCCCCGCAGACCGAAAGGCCCAAGGTGCTGATCCTCGGTTCGGGGCCCAATCGGATCGGCCAGGGTATCGAGTTCGACTACAGCTGCGTACACGCGGCAACCACGTTGAGCCAGGCTGGCTTTGAGACCGTGATGGTCAACTGCAACCCGGAGACGGTGTCCACCGACTACGACACCGCGGACAGGTTGTACTTCGAGCCGTTGACGTTCGAGGACGTCTTGGAGGTCTACCACGCCGAAATGGAATCCGGTAGCGGTGGCCCGGGAGTGGCCGGCGTCATCGTGCAGCTCGGCGGCCAGACCCCGCTCGGGCTGGCGCACCGGCTCGCCGACGCCGGGGTCCCGATCGTGGGCACCCCACCGGAGGCCATCGACCTGGCCGAGGATCGCGGCGCGTTCGGCGACCTGCTGAGCGCCGCCGGACTGCCGGCGCCAAAGTACGGCACCGCAACCACTTTCGCCCAGGCCCGCCGGATCGCCGAGGAGATCGGCTATCCGGTGCTGGTGCGGCCGTCGTATGTGCTCGGTGGTCGCGGCATGGAGATCGTGTATGACGAAGAAACGTTGCAGGGCTACATCACCCGCGCCACTCAGCTATCCCCCGAACACCCGGTGCTCGTCGACCGCTTCCTCGAGGACGCGGTCGAGATCGACGTCGACGCGCTGTGTGATGGCGCCGAGGTCTATATCGGCGGGATCATGGAGCACATCGAGGAGGCCGGCATCCACTCCGGTGACTCGGCCTGTGCGCTGCCACCGGTCACGTTGGGCCGCAGCGACATCGCGAAGGTGCGTAAGGCCACTGAAGCCATTGCGCACGGCATCGGCGTGGTGGGGCTGCTCAACGTGCAGTACGCGCTCAAGGATGACGTGCTCTACGTCCTGGAAGCCAACCCGAGAGCGAGCCGTACCGTTCCGTTTGTATCCAAGGCCACAGCGGTGCCACTCGCCAAGGCATGCGCCCGGATCATGTTGGGCGCCACCATTGCCCAGCTGCGCGCCGAAGGCTTGCTGGCGGTCACCGGGGATGGCGCCCACGCGGCGCGAAACGCCCCCATCGCGGTCAAGGAGGCCGTGTTGCCGTTTCACCGGTTCCGGCGCGCCGACGGGGCCGCCATCGACTCGCTACTCGGCCCGGAGATGAAATCGACCGGCGAGGTGATGGGCATCGACCGCGACTTCGGCAGCGCGTTCGCCAAGAGCCAGACCGCCGCCTACGGGTCGCTGCCGGCCCAGGGCACAGTGTTCGTGTCGGTGGCCAACCGGGACAAGCGGTCGCTGGTGTTTCCGGTCAAACGATTGGCCGACCTGGGTTTTCGCGTCCTTGCCACCGAAGGCACCGCAGAGATGTTGCGCCGCAACGGTATTCCCTGCGACGACGTCCGCAAACATTTCGAGCCGGCGCAGCCCGGCCGCCCCACAATGTCGGCGGTGGACGCGATCCGAGCCGGCGAGGTCAACATGGTGATCAACACTCCCTATGGCAACTCCGGTCCGCGCATCGACGGCTATGAGATCCGTTCGGCGGCGGTGGCCGGCAACATCCCGTGCATCACCACGGTGCAGGGCGCATCCGCCGCCGTGCAGGGGATAGAGGCCGGGATCCGCGGCGACATCGGGGTGCGCTCCCTGCAGGAGCTGCACCGGGTGATCGGGGGCGTCGAGCGGTGA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
CarB family
- GO
-
- metal ion binding GO:0046872 molecular_function
- 'de novo' UMP biosynthetic process GO:0044205 biological_process
- ATP binding GO:0005524 molecular_function
- plasma membrane GO:0005886 cellular_component
- cytoplasm GO:0005737 cellular_component
- carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0004088 molecular_function
- glutamine metabolic process GO:0006541 biological_process
- arginine biosynthetic process GO:0006526 biological_process
- nitrogen compound metabolic process GO:0006807 biological_process
- InterPro
Summary
- Name
- Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase ammonia chain)
- Family
- CarB family
- Protein Sequence
-
MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTALNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESARSRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAGLAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALGKVMRSLETTRAGFWTAPDPDGGIEEALTRLRTPAEGRLYDIELALRLGATVERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSDHQIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSYELDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGVAGVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAAGLPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQGYITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIAKVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRAEGLLAVTGDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAGEVNMVINTPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHRVIGGVER
- Mass
- 118,961 Da
- Length
- 1115 Aa
Rv1384 doesn't seem to be a targeted by any drug.
Rv1384 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.