qor
- Type
- protein_coding
- Name
- qor
- Locus Name
-
Rv1454c
- Product
-
Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1639674..1640660 (- strand)
- Gene Length
- 986 bp
- Nucleotides
-
ATGCACGCAATCGAAGTCACCGAAACCGGCGGGCCAGGCGTCTTACGCCACGTCGACCAGCCGCAACCTCAACCCGGCCACGGCGAGCTCCTGATCAAGGCCGAGGCCATCGGTGTCAACTTCATCGACACCTACTTCCGCTCCGGGCAATATCCGCGCGAACTCCCGTTCGTCATCGGCTCCGAGGTATGCGGCACGGTGGAGGCCGTCGGCCCAGGGGTTACCGCAGCCGACACCGCCATCAGCGTCGGCGACCGCGTGGTCAGCGCCTCAGCCAACGGCGCCTACGCCGAATTCTGCACAGCGCCAGCATCTCTGACCGCCAAGGTCCCCGACGACGTCACGTCTGAGGTAGCGGCTTCGGCGCTGCTGAAGGGCCTGACGGCGCATTACCTACTGAAGTCGGTGTACCCGGTGAAGCGTGGTGACACCGTCTTGGTGCATGCTGGCGCCGGCGGCGTCGGCTTGATCCTGACACAATGGGCCACTCACCTGGGGGTGCGGGTGATCACCACCGTTTCGACGGCGGAGAAGGCCAAGCTGTCCAAGGATGCCGGCGCGGACGTGGTTCTCGACTACCCGGAGGATGCCTGGCAGTTCGCCGGGCGGGTTCGCGAACTGACCGGCGGCACCGGTGTGCAAGCCGTTTACGACGGTGTCGGCGCCACCACCTTCGACGCCAGCCTAGCCAGCCTGGCTGTCCGCGGGACATTAGCACTGTTCGGCGCCGCCAGCGGTCCGGTTCCACCGGTCGATCCGCAGCGCCTCAATGCCGCCGGATCGGTGTACCTCACCCGTCCCTCGCTGTTCCACTTCACCCGCACCGGCGAGGAGTTCAGCTGGCGGGCCGCTGAGCTGTTCGACGCGATCGGCAGCGAAGCGATCACCGTGGCGGTCGGCGGACGTTACCCGCTGGCCGACGCCTTGCGCGCCCATCAGGACCTGGAGGCTCGCAAGACGGTCGGCTCGGTCGTGCTGCTGCCGTA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Unknown
- GO
-
- cellular response to oxidative stress GO:0034599 biological_process
- NADPH:quinone reductase activity GO:0003960 molecular_function
- AU-rich element binding GO:0017091 molecular_function
- cell wall GO:0005618 cellular_component
- extracellular region GO:0005576 cellular_component
- cytosol GO:0005829 cellular_component
- plasma membrane GO:0005886 cellular_component
- cytoplasm GO:0005737 cellular_component
- nucleotide binding GO:0000166 molecular_function
- InterPro
4RVS
- Name
- Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)
- Family
- Unknown
- Protein Sequence
-
MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP
- Mass
- 34,047 Da
- Length
- 328 Aa
Summary
Rv1454c doesn't seem to be a targeted by any drug.
Rv1454c doesn't seem to be involved in any pathway.
- Structural views of quinone oxidoreductase from Mycobacterium tuberculosis reveal large conformational changes induced by the co-factor.
- FEBS J. 2015 Jul;282(14):2697-707. doi: 10.1111/febs.13312. Epub 2015 May 20.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.