Gene - combatTB X

Rv1524

Type: protein_coding
Name: Rv1524
Locus Name: Rv1524
Product: Probable glycosyltransferase
Functional Category: Intermediary metabolism and respiration
Location: 1718726..1719970 (+ strand)
Gene Length: 1244 bp
Nucleotides: TGAAATTTGTCGTGGCCAGCTATGGGACTCGCGGCGACATCGAGCCCTGCGCAGCGGTCGGCCTGGAGCTGCAGCGGCGCGGCCATGATGTGTGCCTTGCCGTGCCGCCCAACCTGATTGGTTTCGTGGAAACGGCCGGGCTGTCTGCTGTCGCATACGGAAGCAGGGACTCTCAGGAGCAGCTCGACGAGCAGTTCCTGCACAACGCGTGGAAACTTCAGAACCCCATCAAGCTGCTGCGTGAAGCGATGGCGCCCGTCACCGAGGGCTGGGCGGAGCTGAGCGCGATGTTGACGCCGGTGGCCGCCGGGGCCGACCTGCTGTTGACCGGTCAGATCTACCAGGAGGTGGTCGCCAACGTCGCCGAGCACCACGGCATTCCGTTGGCCGCGCTGCATTTTTATCCGGTGCGAGCCAATGGCGAGATCGCCTTTCCCGCGCGGCTGCCGGCGCCACTGGTCCGCTCCACCATCACGGCCATCGACTGGCTGTATTGGCGCATGACGAAAGGTGTTGAGGACGCGCAGCGGCGTGAACTGGGCCTGCCGAAGGCGTCAACTCCCGCGCCGCGGCGAATGGCCGTACGCGGGTCGCTGGAGATCCAAGCCTACGACGCGCTTTGCTTCCCGGGGCTGGCAGCGGAATGGGGCGGCCGACGCCCGTTCGTCGGCGCGTTGACGATGGAATCGGCGACCGACGCGGACGACGAGGTCGCTTCATGGATCGCTGCCGATACACCGCCGATTTATTTCGGCTTTGGCAGCATGCCGATCGGATCCCTGGCCGACCGGGTCGCCATGATCAGTGCGGCCTGCGCGGAGTTGGGCGAGCGCGCGTTGATTTGCTCGGGACCCAGCGATGCGACCGGAATCCCGCAGTTCGATCACGTGAAGGTGGTGCGTGTGGTCAGCCACGCGGCGGTCTTTCCCACCTGCCGTGCGGTCGTCCACCATGGCGGCGCGGGCACCACCGCCGCCGGTCTTCGAGCCGGTATCCCCACCTTGATTCTGTGGGTCACCTCCGACCAGCCGATCTGGGCTGCTCAGATCAAACAGCTGAAAGTAGGCCGGGGGAGACGCTTTTCAAGCGCCACCAAAGAATCGCTGATTGCCGACCTTCGAACGATACTTGCGCCGGACTATGTCACCCGAGCGCGGGAGATCGCGTCTCGGATGACCAAACCCGCCGCCAGCGTCACGGCCACCGCCGATCTGCTCGAAGATGCAGCCCGCCGTGCGCGCTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Glycosyltransferase 28 family

GO

lipid glycosylation GO:0030259 biological_process
carbohydrate metabolic process GO:0005975 biological_process
intracellular membrane-bounded organelle GO:0043231 cellular_component
UDP-glycosyltransferase activity GO:0008194 molecular_function
transferase activity, transferring hexosyl groups GO:0016758 molecular_function

InterPro

IPR004276

UniProt: P9WN07
GenBank: Rv1524
EnsemblBacteria: Rv1524
Mycobrowser: Rv1524

Summary

Name: Uncharacterized glycosyltransferase Rv1524 (EC 2.4.-.-)
Family: Glycosyltransferase 28 family
Protein Sequence: MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQFLHNAWKLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWGGRRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR
Mass: 44,362 Da
Length: 414 Aa

Rv1524 doesn't seem to be a targeted by any drug.

Rv1524 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.