Gene - combatTB X

PPE21

Type: protein_coding
Name: PPE21
Locus Name: Rv1548c
Product: PPE family protein PPE21
Functional Category: Pe/ppe
Location: 1751297..1753333 (- strand)
Gene Length: 2036 bp
Nucleotides: ATGAATTTTTCGGTGTTGCCGCCGGAGATCAATTCGGCGCTGATGTTCGCTGGTGCCGGGCCGGGACCGATGTTGGCGGCGGCGTCGGCCTGGACCGGGCTGGCCGGCGATTTGGGTTCGGCGGCGGCCTCATTTTCGGCGGTGACCTCGCAGTTGGCCACCGGGTCCTGGCAAGGTCCGGCGTCAGCGGCCATGACAGGCGTGGCCGCGTCCTATGCTCGCTGGCTGACCACGGCCGCAGCGCAGGCTGAGCAGGCGGCGGGTCAAGCCCAGGCGGCGGTATCGGCGTTCGAGGCGGCGCTGGCGGCGACGGTGCATCCGGGCGCGGTGAGCGCCAATCGAGGTCGGTTGCGCTCCTTGGTGGCCTCGAATCTGTTGGGGCAAAACGCCCCGGCCATCGCGGCCGTCGAGGCCGTCTATGAGCAGATGTGGGCCGCCGATGTCGCCGCGATGCTCGGTTATCACGGCGAGGCGTCGGCGGTCGCCTTGTCGCTGACGCCGTTCACACCGTCGCCGAGCGCGGCAGCCACGCCCGGCGGTGCGGTGATCATCGCGGGGTTTCCGTTTCTCGATCTGGGCAACGTCACCATCGGTGGCTTCAATCTGGCCAGCGGCAATCTGGGCCTCGGCAACCTGGGCAGCTTCAACCCGGGTAGCGCCAACACGGGCAGCGTCAACTTGGGCAACGCCAATATCGGTGATCTCAACCTGGGCAGCGGCAATATCGGCAGCTACAACCTGGGTGGCGGCAACACCGGGGATCTCAACCCGGACAGTGGAAACACGGGCACGCTCAACTGGGGTAGCGGAAACATCGGCAGCTATAACCTGGGCGGCGGCAACCTCGGCAGCTATAACCTGGGTAGTGGAAATACCGGCGACACCAACTTTGGCGGCGGTAACACCGGAAATCTCAACGTGGGTGGCGGCAACACCGGGAACTCGAATTTCGGGTTCGGAAACACCGGTAACGTCAACTTTGGTAACGGAAACACCGGCGACACCAACTTTGGCAGCGGCAACCTTGGCAGTGGAAATATCGGTTTCGGCAACAAGGGCTCTCATAACATCGGGTTTGGGAACAGCGGCAACAACAACATCGGCTTCGGGCTCACCGGTGATAACCAGATAGGTTTCGGCGCCCTCAATTCAGGTAGCGGGAACCTCGGCTTCGGGAACTCGGGCAACGGTAATATCGGCTTTTTCAACTCGGGCAATAACAACATCGGCATGGGAAACTCGGGCAATGGAGTCGGGGCGCTGAGCGTGGAGTTCGGCAGTTCGGCCGAGCGCAGCTCGGGCTTCGGCAACTCCGGCGAGCTCAGTACCGGTATCGGCAACTCCGGCCAGCTCAGCACGGGCTGGTTCAACTCGGCCACCACCAGCACCGGCTGGTTCAACTCCGGCACCACCAATACCGGCTGGTTCAACTCGGGCACCACGAACACCGGAATCGGAAACTCGGGCGGAAACCTGGTCACCGGCAGCATGGGTCTGTTTAACTCCGGCCATACCAACACGGGTAGCTTCAATGCCGGCAGCATGAACACGGGCGATTTCAACTCGGGCAACGTGAACACCGGCTACTTCAACTCCGGCAACATCAACACCGGCTTCTTCAACTCGGGCGATCTCAACACCGGATTGTTCAACTCGGTCAACCAGCCGGTACAGAACTCCGGCTGGCTGCACACGGGCACCAACAACTCGGGCTACGCTAACGCCGGCACCTTCAACTCGGGCTTCGATAACAACGCCCGTGACGAACACGCCGAATTTGTCACCGGTAACTCGGGCCTGGCCAACGTGGGCAACTACAACGCCGGCATCATCAACGTGGGTGACCATCTGTCGGGCTTCAGAAACTCGGTACCCACGATCACCGGTACGGCCAACATTTCGGGTTTCGTCAATGCGGGAACCTCGATCTCTGGCTTCTTCAACTTCGGCAGCCTCATGTCGGGCTTCGCCAACTTCGACGACGAGGTCTCGGGGTATCTCAACGGGGACAGTCGGGCGTCGGGCTGGATCCATTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PPE family

GO

plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: P9WI21
GenBank: Rv1548c
EnsemblBacteria: Rv1548c
Mycobrowser: Rv1548c

Summary

Name: Uncharacterized PPE family protein PPE21
Family: Mycobacterial PPE family
Protein Sequence: MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSGNIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIGFFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGTTNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAGTSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
Mass: 66,737 Da
Length: 678 Aa

Rv1548c doesn't seem to be a targeted by any drug.

Rv1548c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.