frdC



Type
protein_coding
Name
frdC
Locus Name

Rv1554

Product

Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogenase) (fumaric hydrogenase)

Functional Category

Intermediary metabolism and respiration

Location
1760175..1760555 (+ strand)
Gene Length
380 bp
Nucleotides
TGAGCGCCTATCGCCAGCCGGTCGAAAGATACTGGTGGGCGAGGCGGCGTTCTTACCTGCGATTCATGCTTCGCGAAATCAGTTGCATCTTCGTGGCCTGGTTTGTTCTCTATCTGATGCTGGTATTGCGCGCCGTTGGCGCGGGCGGGAATTCCTACCAGCGGTTTTTGGACTTCAGCGCCAATCCGGTTGTCGTAGTGCTGAACGTCGTCGCGTTGAGTTTCCTGCTGCTGCATGCTGTTACCTGGTTCGGATCGGCACCGCGCGCGATGGTGATTCAGGTTCGCGGCCGCCGGGTACCCGCTCGCGCGGTCCTTGCTGGGCACTACGCGGCATGGCTGGTGGTTTCGGTGATCGTTGCCTGGATGGTGCTGTCATGA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00708}.
Family

FrdC family

GO
InterPro

UniProt
P9WNB7
GenBank
Rv1554
EnsemblBacteria
Rv1554
Mycobrowser
Rv1554


Summary
Name
Fumarate reductase subunit C
Family
FrdC family
Protein Sequence
MSAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFSANPVVVVLNVVALSFLLLHAVTWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIVAWMVLS
Mass
14,449 Da
Length
126 Aa

Rv1554 doesn't seem to be a targeted by any drug.



Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.