Gene - combatTB X

mmpL6

Type: protein_coding
Name: mmpL6
Locus Name: Rv1557
Product: Probable conserved transmembrane transport protein MmpL6
Functional Category: Cell wall and cell processes
Location: 1761744..1762937 (+ strand)
Gene Length: 1193 bp
Nucleotides: TGCAGGGGATTTCAGTGACTGGCCTGGTCAAACGCGGCTGGATGGTGAGATCCGTCTTTGACACGATCGACGGTATCGACCAACTCGGCGAGCAGCTGGCCAGCGTGACCGTAACCTTGGACAAGTTGGCTGCGATCCAGCCTCAATTGGTGGCGCTGCTACCAGACGAGATCGCCAGCCAGCAGATCAATCGGGAACTGGCGCTGGCTAACTACGCCACCATGTCCGGGATCTATGCCCAGACGGCGGCCTTGATCGAAAACGCTGCCGCCATGGGACAAGCCTTTGACGCCGCCAAGAACGACGACTCCTTCTATCTGCCGCCGGAGGCTTTTGACAACCCAGATTTCCAGCGCGGCCTGAAATTGTTCCTGTCGGCAGACGGTAAGGCGGCTCGGATGATCATCTCCCATGAAGGCGATCCCGCCACCCCCGAAGGCATTTCGCATATCGACGCGATCAAGCAGGCGGCCCACGAGGCCGTGAAGGGCACTCCCATGGCGGGTGCTGGGATCTATCTGGCCGGCACGGCCGCCACCTTCAAGGACATTCAAGACGGCGCCACCTACGACCTCCTGATCGCCGGAATAGCCGCGCTGAGCTTGATTTTGCTCATCATGATGATCATTACCCGAAGCCTGGTTGCGGCGCTGGTGATCGTGGGCACGGTGGCGCTGTCGTTGGGCGCTTCTTTTGGCCTGTCCGTGCTGGTGTGGCAGCATCTTCTCGGTATCCAGTTGTACTGGATCGTGCTCGCGCTGGCCGTCATCCTGCTCCTGGCCGTGGGATCGGACTATAACTTGCTGCTGATTTCCCGATTCAAGGAGGAGATCGGTGCAGGTTTGAACACCGGCATCATCCGTGCGATGGCCGGCACCGGCGGGGTGGTGACCGCTGCCGGCCTGGTGTTCGCCGCCACTATGTCTTCGTTCGTGTTCAGTGATTTGCGGGTCCTCGGTCAGATCGGGACCACCATTGGTCTTGGGCTGCTGTTCGACACGCTGGTGGTGCGCGCGTTCATGACCCCGTCCATCGCGGTGCTGCTCGGGCGCTGGTTCTGGTGGCCGCAACGAGTGCGCCCGCGCCCTGCCAGCAGGATGCTTCGGCCGTACGGCCCGCGGCCCGTGGTTCGTGAATTGCTGCTGCGCGAGGGCAACGATGACCCGAGAACTCAGGTGGCTACCCACCGTTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Resistance-nodulation-cell division (RND) (TC 2.A.6) family, MmpL subfamily

GO

response to organic substance GO:0010033 biological_process
plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR004869

UniProt: P9WJU9
GenBank: Rv1557
EnsemblBacteria: Rv1557
Mycobrowser: Rv1557

Summary

Name: Probable transport protein MmpL6
Family: Resistance-nodulation-cell division (RND) (TC 2.A.6) family, MmpL subfamily
Protein Sequence: MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Mass: 42,422 Da
Length: 397 Aa

Rv1557 doesn't seem to be a targeted by any drug.

Rv1557 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.