hisC1
- Type
- protein_coding
- Name
- hisC1
- Locus Name
-
Rv1600
- Product
-
Probable histidinol-phosphate aminotransferase HisC1
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 1800896..1802038 (+ strand)
- Gene Length
- 1142 bp
- Nucleotides
-
TGACCAGGTCCGGACACCCGGTTACATTGGACGACTTGCCGCTGCGCGCCGACTTGCGTGGTAAAGCACCATACGGTGCACCGCAATTAGCTGTTCCGGTACGGCTGAACACCAACGAGAACCCGCACCCGCCTACCCGGGCGCTGGTTGACGACGTGGTGCGATCGGTGCGGGAAGCGGCCATCGACTTGCACCGCTACCCCGACCGCGACGCCGTGGCTCTGCGTGCTGACTTGGCCGGCTATCTCACCGCGCAGACCGGAATCCAGCTTGGTGTCGAAAACATATGGGCTGCCAACGGTTCCAATGAGATTCTGCAGCAACTGTTACAGGCGTTTGGCGGTCCGGGGCGTAGCGCGATCGGTTTCGTACCGTCCTATTCGATGCACCCGATCATCTCCGACGGCACCCACACGGAATGGATCGAGGCGTCCCGCGCCAATGACTTCGGTCTCGACGTGGACGTCGCCGTCGCGGCTGTGGTCGATCGCAAACCCGATGTGGTGTTCATTGCTAGCCCTAACAACCCGTCCGGACAAAGTGTTTCGTTACCTGACCTGTGTAAGCTGCTGGACGTTGCGCCCGGAATTGCGATCGTCGACGAGGCCTACGGCGAGTTCTCCTCGCAGCCCAGCGCGGTGTCGCTGGTCGAGGAGTATCCGAGCAAGCTCGTCGTCACGCGCACCATGAGCAAGGCATTCGCTTTCGCCGGCGGCAGGCTCGGATACCTGATCGCTACGCCCGCGGTGATCGACGCAATGCTGCTGGTGCGGTTGCCGTATCACCTGTCGTCGGTCACTCAAGCCGCGGCCCGGGCCGCGCTGCGGCACTCCGACGACACCTTGAGCAGTGTCGCCGCACTGATCGCCGAACGCGAACGCGTAACAACCTCATTGAACGACATGGGTTTTCGAGTCATCCCAAGCGATGCCAACTTCGTGTTGTTCGGCGAGTTTGCCGATGCGCCGGCCGCCTGGCGGCGCTATCTGGAGGCCGGCATTTTGATCCGCGACGTTGGGATTCCCGGCTATCTGCGGGCCACCACCGGGCTGGCTGAGGAGAACGATGCGTTCCTGCGGGCAAGCGCCCGGATCGCCACCGACCTGGTCCCCGTCACCCGCAGTCCTGTAGGAGCGCCATGA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Class-II pyridoxal-phosphate-dependent aminotransferase family, Histidinol-phosphate aminotransferase subfamily
- GO
-
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- pyridoxal phosphate binding GO:0030170 molecular_function
- histidine biosynthetic process GO:0000105 biological_process
- histidinol-phosphate transaminase activity GO:0004400 molecular_function
- InterPro
- Name
- Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase)
- Family
- Class-II pyridoxal-phosphate-dependent aminotransferase family, Histidinol-phosphate aminotransferase subfamily
- Protein Sequence
-
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
- Mass
- 40,581 Da
- Length
- 380 Aa
Rv1600 doesn't seem to be a targeted by any drug.
-
-
Phenylalanine, tyrosine and tryptophan biosynthesis mtu00400
mtu00400PATHWAY_MAP mtu00400 Phenylalanine, tyrosine and tryptophan biosynthesis
-
-
-
Phenylalanine metabolism mtu00360
mtu00360PATHWAY_MAP mtu00360 Phenylalanine metabolism
-
-
-
Tyrosine metabolism mtu00350
mtu00350PATHWAY_MAP mtu00350 Tyrosine metabolism
-
-
-
Histidine metabolism mtu00340
mtu00340PATHWAY_MAP mtu00340 Histidine metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.