Gene - combatTB X

Rv1635c

Type: protein_coding
Name: Rv1635c
Locus Name: Rv1635c
Product: Probable mannosyltransferase. Probable conserved transmembrane protein.
Functional Category: Cell wall and cell processes
Location: 1840572..1842242 (- strand)
Gene Length: 1670 bp
Nucleotides: ATGCATGCGAGTCGTCCCGGCGCACCGCCGCACGCCGGGCTGCCCAGTCGCCGAACCGCCGGTGACCAGGATCATCGCGCGGACCCTAAGGTGACCCGCATCATGTCCGCCTCCACTCTGGAGCAGCCCGCGGCAGCACACGTCGACGAGTTGGTGGCGCGGATGCGCGGCCGGCTGCTCGACCCGCTGGCGATTGCAGTGCTGGCCGCGGTCATCAGCGGCGCCTGGGCAAGCAGGCCATCGTTGTGGTTCGACGAGGGGGCAACGATCTCGGCTTCAGCCAGCCGGACATTGCCAGAGCTATGGAGTCTGCTGGGCCATATCGACGCCGTGCACGGCCTGTACTACCTGTTGATGCATGGCTGGTTCGCCATATTTCCGCCCACCGAATTATGGTCGCGGCTTCCCAGCTGCCTGGCCATTGGAGCGGCCGCCGCCGGCGTGGTGGTTTTTGCCAAACAGTTTTCGGGACGCACCACGGCGGTGTGTGCGGGAGCCGTGTTCGCGATTCTGCCCAGGGTGACGTGGGCCGGAATCGAAGCACGCTCCTCCGCGCTGTCGGTAGCAGCCGCCGTCTGGCTGACCGTATTACTCGTGGCCGCGGTGCGGTGCAACACCCAGCGGCGGTGGCTGCTCTACGCGCTGGTTTTGATGCTGTCGATCTTGGTCAGTATCAACCTGGCCCTGTTGGTACCGGCCTATGCGACGATGGTGCCGCTGCTGGCGTCCGGGAAATCACGCAAATCTCCCGTGATCTGGTGGACGGTCGTCACGGCAGCCGCGCTCGGGGCCATGACACCGTTCATACTGTTCGCCCACGGCCAGGTTTGGCAGGTCGGGTGGATCGCAGGGTTGAACAGAAACATCATTCTCGACGTCATACACCGCCAGTATTTCGATCACAGTGTTCCGTTCGCCATCCTCGCGGGCCTCATCGTCGCTGCCGGCATCGCGGCGCATCTGGCCGGAGCTCGTGGACCCGGTGGCGATACCCACCGGCTCGTGCTCGTCAGCGCAGCCTGGATCGTCGTGCCCACCGCCGTCGTCCTCATCTACTCGGCGACCGTCGAACCGATCTACTACCCGCGCTACCTGATCCTCACCGCCCCCGCCGCGGCCGTCATCCTGGCGGTTTGCGTCGTCACCATCGCCCGCAAGCCGTGGCTCATCGCCGGGGTCGTGTTTCTCCTTGCCGCCGCAGCGTTTCCGAACTACTTCTTCACACAGCGGGGGCCGTACGCGAAAGAGGGCTGGGATTACAGCCAGGTGGCAGATGTCATCAGCGCCCATGCCAAGCCCGGGGATTGCCTGCTGGTGGACAACACCGCGGGTTGGCGACCCGGGCCCATCCGCGCCCTGCTGGCCACCCGGCCGGCGGCGTTCCGGTCGCTGATTGACGTCGAGCGCGGCACCTACGGCCCCAAGGTCGGCACTTTGTGGGATGGCCATGTCGCTGTGTGGCTTACGACGGCCAAGATCGACAAGTGCCCCACGCTGTGGACGATAGCCAATCGTGACAAGTCGTTGCCCGATCATCAGGTCGGCGAAATGTTGTCACCGGGAACAGGCTTCGGGCGCACGCCCGTATACCGGTTCCCGAGCTACCTCGGCTTCCGCATCGTCGAGCGCTGGCAGTTCCACTACTCGCAGGTGGTCAAGTCAACGCGGTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

extracellular region GO:0005576 cellular_component
transferase activity, transferring glycosyl groups GO:0016757 molecular_function
integral component of membrane GO:0016021 cellular_component

InterPro

IPR038731

UniProt: O06152
GenBank: Rv1635c
EnsemblBacteria: Rv1635c
Mycobrowser: Rv1635c

Summary

Name: Probable mannosyltransferase. Probable conserved transmembrane protein
Family: Unknown
Protein Sequence: MHASRPGAPPHAGLPSRRTAGDQDHRADPKVTRIMSASTLEQPAAAHVDELVARMRGRLLDPLAIAVLAAVISGAWASRPSLWFDEGATISASASRTLPELWSLLGHIDAVHGLYYLLMHGWFAIFPPTELWSRLPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWAGIEARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVSINLALLVPAYATMVPLLASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQVWQVGWIAGLNRNIILDVIHRQYFDHSVPFAILAGLIVAAGIAAHLAGARGPGGDTHRLVLVSAAWIVVPTAVVLIYSATVEPIYYPRYLILTAPAAAVILAVCVVTIARKPWLIAGVVFLLAAAAFPNYFFTQRGPYAKEGWDYSQVADVISAHAKPGDCLLVDNTAGWRPGPIRALLATRPAAFRSLIDVERGTYGPKVGTLWDGHVAVWLTTAKIDKCPTLWTIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRIVERWQFHYSQVVKSTR
Mass: 60,035 Da
Length: 556 Aa

Rv1635c doesn't seem to be a targeted by any drug.

Lipoarabinomannan (LAM) biosynthesis mtu00571
mtu00571
Metabolism; Glycan biosynthesis and metabolism

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.