cmr
- Type
- protein_coding
- Name
- cmr
- Locus Name
-
Rv1675c
- Product
-
Probable transcriptional regulatory protein Cmr
- Functional Category
-
Regulatory proteins
- Location
- 1900241..1900975 (- strand)
- Gene Length
- 734 bp
- Nucleotides
-
ATGGCAGATCGGTCGGTGCGCCCGCTGCGGCATCTCGTTCATGCGGTGACTGGGGGCCAACCGCCTTCCGAGGCCCAGGTCCGACAGGCAGCCTGGATTGCGCGGTGCGTCGGTCGCGGAGGCTCGGCGCCACTGCACCGTGACGATGTGTCGGCATTGGCCGAAACGTTACAAGTCAAGGAGTTTGCCCCCGGGGCAGTGGTATTCCACGCCGATCAAACCGCGGACGGGGTGTGGATTGTGCGACACGGATTAATTGAGCTCGCGGTCGGCTCCAGGCGGCGCCGCGCCGTGGTGAACATCCTTCATCCCGGCGATGTCGATGGCGACATCCCGCTGCTACTGGAGATGCCGATGGTCTACACGGGGCGCGCCTTGACCCAAGCGACCTGCCTGTTCCTGGACCGGCAGGCGTTCGAGCGGCTGCTAGCTACCCACCCGGCCATCGCACGGCGGTGGCTGTCGAGTGTGGCGCAACGGGTGTCGACTGCGCAGATTCGGTTAATGGGCATGCTTGGCCGCCCGCTGCCCGCGCAGGTTGCGCAGCTCCTGCTCGACGAGGCAATCGATGCCCGTATCGAACTTGCCCAACGCACCCTCGCCGCAATGCTTGGAGCGCAGCGCCCATCGATCAACAAGATTCTCAAGGAGTTCGAGCGCGACCGATTGATCACCGTCGGGTATGCGGTCATCGAGATCACCGACCAACACGGATTACGCGCCCGGGCTCAATG
- Drug Resistance
- Mutations
- Function
- Positively regulates the expression of at least groEL2. Cyclic AMP does not affect transcription in vitro. {ECO:0000269|PubMed:22464736}.
- Family
-
Unknown
- GO
-
- DNA-binding transcription factor activity GO:0003700 molecular_function
- cytosol GO:0005829 cellular_component
- DNA binding GO:0003677 molecular_function
- regulation of transcription, DNA-templated GO:0006355 biological_process
- InterPro
Summary
- Name
- HTH-type transcriptional regulator Cmr
- Family
- Unknown
- Protein Sequence
-
MADRSVRPLRHLVHAVTGGQPPSEAQVRQAAWIARCVGRGGSAPLHRDDVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAVVNILHPGDVDGDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRVSTAQIRLMGMLGRPLPAQVAQLLLDEAIDARIELAQRTLAAMLGAQRPSINKILKEFERDRLITVGYAVIEITDQHGLRARAQ
- Mass
- 26,793 Da
- Length
- 244 Aa
Rv1675c doesn't seem to be a targeted by any drug.
Rv1675c doesn't seem to be involved in any pathway.
- Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2.
- Tuberculosis (Edinb). 2012 Jul;92(4):328-32. doi: 10.1016/j.tube.2012.03.001. Epub 2012 Mar 29.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.