Gene - combatTB X

recN

Type: protein_coding
Name: recN
Locus Name: Rv1696
Product: Probable DNA repair protein RecN (recombination protein N)
Functional Category: Information pathways
Location: 1919683..1921446 (+ strand)
Gene Length: 1763 bp
Nucleotides: TGTTGACTGAATTACGGATCGAGTCGCTGGGCGCCATCAGCGTTGCCACCGCTGAGTTCGATCGCGGCTTTACCGTGCTGACCGGGGAGACCGGCACCGGCAAGACCATGGTGGTGACCGGGCTGCACCTACTTGGTGGTGCCCGGGCCGATGCAACTCGCGTTCGGTCCGGTGCTGACCGTGCCGTTGTCGAAGGGCGTTTTACTACAACCGATCTCGACGACGCGACCGTCGCGGGGCTGCAGGCGGTTCTCGACTCGTCGGGGGCCGAGCGCGACGAGGACGGCAGCGTGATCGCGTTGCGCTCGATCAGTCGCGATGGACCGTCGCGCGCCTACCTCGGCGGCCGCGGTGTACCCGCCAAATCGTTGAGCGGTTTCACGAACGAGCTGCTTACTCTGCACGGGCAGAACGACCAGCTGCGGTTGATGCGCCCGGACGAACAACGTGGTGCACTGGACCGCTTTGCGGCCGCTGGCGAAGCCGTCCAGCGTTACCGCAAGCTGCGGGATGCCTGGCTAACGGCCCGACGCGACCTCGTCGACCGTCGCAACCGGGCCCGGGAACTAGCGCAAGAGGCCGATCGGCTGAAATTCGCGCTCAACGAGATCGACACCGTCGACCCGCAGCCGGGGGAGGACGTGGCGTTGGTCGCCGACATCGCCCGGCTTTCCGAACTGGACACCCTGCGGGAGGCCGCGACTACTGCACGCGCGACGTTGTGCGGGACACCAGACGCGGACGCATTCGACCGCGGCGCCGTCGACAGCCTCGGGCGGGCACGTGCGGCACTGCAATCGAGCGATGATGCCGCGTTGCGGGGGTTGGCCGAACAGGTCGGTGAGGCGTTGACGGTGGTCGTCGATGCGGTCGCCGAGCTCGGCGCCTACCTGGACGAGCTGCCCGCCGACGCCAGCGCGCTGGACGCCAAGCTGGCGCGCCAAGCCCAGCTGCGAACGTTAACCCGCAAGTACGCCGCCGACATCGATGGCGTGCTCCGGTGGGCGGATGAGGCGAGGGCAAGGCTGGCTCAACTCGACGTCTCCGAAGAAGGGCTGGCAGCGCTGGAACGCCGTACCGGTGAGCTCGCCCACGAATTAGGCCAAGCCGCAGTTGATCTCAGCACGATCCGGCGGAAGGCGGCCAAGCGGCTGGCCAAGGAGGTCAGCGCGGAGCTGTCCGCCCTGGCGATGGCCGATGCCGAATTCACCATCGGTGTGACCACAGAGCTGGCCGACCACGGCGATCCCGTCGCCTTGGCCCTGGCGTCGGGCGAATTGGCCCGGGCCGGTGCCGATGGCGTCGATGCGGTCGAGTTCGGTTTCGTCGCACACCGGGGGATGACAGTGCTGCCGCTGGCCAAGAGCGCATCCGGCGGCGAACTGTCCCGGGTGATGTTGTCCCTGGAGGTGGTGCTGGCTACTTCGCGAAAACAAGCGGCTGGCACCACGATGGTGTTCGACGAGATCGACGCCGGCGTCGGCGGCTGGGCTGCGGTACAGATCGGGCGGCGGCTGGCGCGGTTGGCTCGCACCCACCAGGTCATCGTGGTCACCCATCTGCCGCAGGTCGCCGCCTATGCCGATGTGCACTTGATGGTGCAGCGCACCGGGCGCGACGGTGCCAGCGGTGTGCGGCGCCTGACCAGCGAGGATCGGGTGGCCGAGCTGGCACGGATGCTGGCCGGGCTTGGTGATTCCGACAGTGGTCGCGCGCACGCGCGGGAGTTACTCGAGACCGCGCAGAACGACGAGCTCACCTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

May be involved in recombinational repair of damaged DNA. {ECO:0000250}.

Family

RecN family

GO

SOS response GO:0009432 biological_process
double-strand break repair via homologous recombination GO:0000724 biological_process
response to radiation GO:0009314 biological_process
cell wall GO:0005618 cellular_component
ATP binding GO:0005524 molecular_function

InterPro

UniProt: P9WHI7
GenBank: Rv1696
EnsemblBacteria: Rv1696
Mycobrowser: Rv1696

Summary

Name: DNA repair protein RecN (Recombination protein N)
Family: RecN family
Protein Sequence: MLTELRIESLGAISVATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGARADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSVIALRSISRDGPSRAYLGGRGVPAKSLSGFTNELLTLHGQNDQLRLMRPDEQRGALDRFAAAGEAVQRYRKLRDAWLTARRDLVDRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALVADIARLSELDTLREAATTARATLCGTPDADAFDRGAVDSLGRARAALQSSDDAALRGLAEQVGEALTVVVDAVAELGAYLDELPADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLAQLDVSEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAMADAEFTIGVTTELADHGDPVALALASGELARAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEVVLATSRKQAAGTTMVFDEIDAGVGGWAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLMVQRTGRDGASGVRRLTSEDRVAELARMLAGLGDSDSGRAHARELLETAQNDELT
Mass: 62,229 Da
Length: 587 Aa

Rv1696 doesn't seem to be a targeted by any drug.

Rv1696 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.