Gene - combatTB X

cycA

Type: protein_coding
Name: cycA
Locus Name: Rv1704c
Product: Probable D-serine/alanine/glycine transporter protein CycA
Functional Category: Cell wall and cell processes
Location: 1929786..1931456 (- strand)
Gene Length: 1670 bp
Nucleotides: ATGCCGGACGATATCGCGGCTGCCGACCCGACAGACACCCAGCCGCACCTGCGTCGGGACCTTGCCAACCGCCATATTCAGTTGATCGCGATTGGAGGCGCGATCGGCACCGGCCTATTCATGGGATCTGGGCGAACGATCTCGCTCGCCGGTCCGGCGGTCATGGTGGTCTACGGGATCATTGGGTTTTTTGTGTTTTTTGTGTTGCGCGCGATGGGCGAGCTGCTGCTGTCGAACCTGAACTACAAGTCGTTCGTTGACTTCGCCGCCGACCTCCGGGGCCCGGCGGCGGGCTTTTTCGTGGGGTGGTCGTACTGGTTCGCATGGGTGGTCACCGGGATCGCAGACCTCGTCGCGATCACCGGCTATGCCAGGTTTTGGTGGCCCGGCTTGCCAATCTGGGTCCCGGCCCTGGTCACGGTCGCCCTGATTCTCGCTGTCAATTTGTTCAGCGTCCGCCACTTCGGGGAGCTGGAGTTTTGGTTCGCATTGATCAAGGTCGCTGCCATCGTGTGCCTCATCGCCGTCGGCGCGATCCTGGTGGCAACCAACTTCGTCTCCCCTCATGGTGTGCACGCGACCATCGAGAACCTGTGGAACGACAACGGGTTCTTCCCAACGGGTTTCCTGGGCGTGGTCAGTGGCTTTCAGATCGCGTTTTTCGCATACATCGGTGTGGAGCTCGTTGGCACCGCCGCGGCTGAGACAGCGGACCCGCGCCGCACCCTTCCCCGCGCGATCAATGCCGTGCCGTTGCGGGTCGCGGTGTTCTACATCGGTGCCCTGCTGGCGATCCTGGCCGTCGTGCCGTGGCGGCAGTTCGCCAGTGGCGAGTCCCCGTTTGTGACGATGTTCTCCCTAGCCGGACTTGCCGCTGCGGCGTCGGTCGTCAACTTCGTCGTGGTCACCGCAGCGGCCTCGTCAGCGAACTCCGGCTTCTTCTCCACCGGGCGAATGCTTTTCGGCCTCGCCGACGAAGGCCACGCTCCGGCCGCTTTCCACCAACTCAATCGCGGCGGCGTGCCCGCACCCGCCCTGCTGCTGACGGCTCCGCTACTGCTGACCTCCATCCCGCTGCTCTATGCCGGTCGGTCGGTGATTGGGGCGTTCACACTCGTCACGACGGTCTCATCCCTGCTGTTCATGTTTGTGTGGGCAATGATCATCATCAGCTACCTCGTCTACCGTCGCCGACACCCACAGCGTCACACCGACTCGGTGTACAAGATGCCCGGTGGCGTGGTGATGTGCTGGGCCGTGCTGGTGTTTTTCGCGTTCGTGATCTGGACACTTACCACCGAAACCGAAACCGCAACCGCGTTGGCGTGGTTCCCGCTATGGTTCGTGCTGCTCGCCGTGGGTTGGCTCGTCACCCAGCGCCGGCAGAGCCGCCGCAGCTTTGGTTTTCACTGCCAGGTCGTCGGGGTTCGTCAGCAGCTCGGCCGCGGTATGGCCAGGCTTGCAATGAAAATCCACGCGCGGCCCAAACTCCGAAGTGCGGTCGTCGTCGAGCCAGTGTCAGCAGGTGAACCAGGTGCCCGCAGGTCCGCGAAATCTGTGCGTAAGCTAGCGAGCGATGATTCGCAAAGCGCGCATTGCCCCGTTGCGGTGGTCGGTCTGGCGGATGGCGGCCGGGATCCGCAATATCACCACGACGGGCCAGATCGGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

transmembrane transporter activity GO:0022857 molecular_function
cytosol GO:0005829 cellular_component
plasma membrane GO:0005886 cellular_component
amino acid transport GO:0006865 biological_process
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: O33203
GenBank: Rv1704c
EnsemblBacteria: Rv1704c
Mycobrowser: Rv1704c

Summary

Name: Probable D-serine/alanine/glycine transporter protein CycA
Family: Unknown
Protein Sequence: MPDDIAAADPTDTQPHLRRDLANRHIQLIAIGGAIGTGLFMGSGRTISLAGPAVMVVYGIIGFFVFFVLRAMGELLLSNLNYKSFVDFAADLRGPAAGFFVGWSYWFAWVVTGIADLVAITGYARFWWPGLPIWVPALVTVALILAVNLFSVRHFGELEFWFALIKVAAIVCLIAVGAILVATNFVSPHGVHATIENLWNDNGFFPTGFLGVVSGFQIAFFAYIGVELVGTAAAETADPRRTLPRAINAVPLRVAVFYIGALLAILAVVPWRQFASGESPFVTMFSLAGLAAAASVVNFVVVTAAASSANSGFFSTGRMLFGLADEGHAPAAFHQLNRGGVPAPALLLTAPLLLTSIPLLYAGRSVIGAFTLVTTVSSLLFMFVWAMIIISYLVYRRRHPQRHTDSVYKMPGGVVMCWAVLVFFAFVIWTLTTETETATALAWFPLWFVLLAVGWLVTQRRQSRRSFGFHCQVVGVRQQLGRGMARLAMKIHARPKLRSAVVVEPVSAGEPGARRSAKSVRKLASDDSQSAHCPVAVVGLADGGRDPQYHHDGPDR
Mass: 60,047 Da
Length: 556 Aa

Rv1704c doesn't seem to be a targeted by any drug.

Rv1704c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.