Gene - combatTB X

scpA

Type: protein_coding
Name: scpA
Locus Name: Rv1709
Product: Possible segregation and condensation protein ScpA
Functional Category: Cell wall and cell processes
Location: 1937313..1938149 (+ strand)
Gene Length: 836 bp
Nucleotides: TGAACGGCCTTCAGAACAGCCTGGCGAACGGTGGGACGGCACCCGAGAACGGCTACTCGGCTGGTTTTCGGGTCCGGCTGACCAACTTCGAGGGCCCGTTCGACCTGCTGCTGCAGCTGATCTTTGCGCACCAACTCGACGTCACCGAAGTGGCGTTGCACCAGGTCACCGACGACTTCATCGCCTACACCAAAGCGATCGGCGCTCGGCTGGAACTAGAGGAGACCACAGCGTTCCTGGTGATCGCCGCAACCTTGCTCGATCTCAAAGCAGCCCGGCTCCTGCCAGCCGGACAGGTCGACGACGAGGAAGACCTCGCGCTTCTGGAGGTACGCGACCTGCTGTTTGCCCGGCTGCTGCAATACCGGGCGTTTAAGCACGTCGCAGAGATGTTCGCCGAACTGGAGGCCACCGCGCTGCGCAGCTATCCACGGGCGGTGTCGTTGGAGGACGGGTTCGTCGGTCTGCTTCCCGAGGTAATGCTCGGCGTTGACGCTCACCGGTTCGCCGAAATCGCTGCGATCGCATTAACCCCGCGGCCAGCCCCGACGGTGGCCACCGAGCACCTGCACGAGTTGATGGTCTCGGTTCCCGAGCAGGCCGAACACTTGCTGGCGATGCTGAAAGCGCGGGGCAGCGGCCAGTGGGCGTCATTTTCGGAGCTGGTCGCCGACTGCACGGCGCCCATCGAGATCGTGGGGCGCTTCCTGGCGCTGCTCGAACTGTATCGGACCCGGGCGGTAGCATTCGAGCAGTCAGAGCCGCTTGGCGCGCTCCAGGTTTCGTGGACCGGTGACGATGCAGAGCGCAGCGATGAGAAGGAGCGGCGCTTGTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. {ECO:0000256|SAAS:SAAS00952070}.

Family

ScpA family

GO

cell cycle GO:0007049 biological_process
chromosome segregation GO:0007059 biological_process
cytoplasm GO:0005737 cellular_component
cell division GO:0051301 biological_process

InterPro

IPR003768

UniProt: O33208
GenBank: Rv1709
EnsemblBacteria: Rv1709
Mycobrowser: Rv1709

Summary

Name: Segregation and condensation protein A
Family: ScpA family
Protein Sequence: MNGLQNSLANGGTAPENGYSAGFRVRLTNFEGPFDLLLQLIFAHQLDVTEVALHQVTDDFIAYTKAIGARLELEETTAFLVIAATLLDLKAARLLPAGQVDDEEDLALLEVRDLLFARLLQYRAFKHVAEMFAELEATALRSYPRAVSLEDGFVGLLPEVMLGVDAHRFAEIAAIALTPRPAPTVATEHLHELMVSVPEQAEHLLAMLKARGSGQWASFSELVADCTAPIEIVGRFLALLELYRTRAVAFEQSEPLGALQVSWTGDDAERSDEKERRL
Mass: 30,569 Da
Length: 278 Aa

Rv1709 doesn't seem to be a targeted by any drug.

Rv1709 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.