Gene - combatTB X

scpB

Type: protein_coding
Name: scpB
Locus Name: Rv1710
Product: Possible segregation and condensation protein ScpB
Functional Category: Cell wall and cell processes
Location: 1938146..1938841 (+ strand)
Gene Length: 695 bp
Nucleotides: TGACCGAACATATGCCCGAACACGATCCGAGCTATGGCATCCCGGATATCGCTGAGCCCGCGGAGCTGGATGCCGACGAGCTTAAGCGTGTGCTAGAGGCGCTGCTGTTGGTGATCGACACCCCAGTGACAGCCGACGCGTTGGCCGCGGCCACCGAACAGCCGGTCTACCGGGTTGCGGCAAAGCTACAGTTGATGGCCGACGAGCTCACCGGGCGTGACAGCGGCATCGACCTGCGCCACACGAGCGAGGGTTGGCGGATGTACACCCGCGCCCGATTCGCGCCCTATGTCGAGAAGCTGTTGCTGGACGGCGCGCGAACCAAGCTCACCCGGGCCGCGCTGGAGACCCTGGCCGTGGTGGCCTACCGCCAGCCGGTCACACGAGCGCGGGTTAGTGCGGTGCGCGGGGTCAACGTGGACGCCGTGATGCGTACGCTGTTGGCCCGCGGCCTGATCACCGAGGTTGGTACCGACGCCGATACCGGCGCGGTGACGTTCGCCACCACCGAGCTCTTCCTGGAGCGCTTGGGATTGACGTCGCTGTCGGAGCTGCCCGATATCGCACCGCTGCTTCCCGACGTCGACACAATTGACGACCTGAGCGAATCCCTGGACAGTGAGCCACGTTTCATCAAACTCACCGGTGAGCTGGCGTCCGAGCAGACGCTGTCGTTCGACGTGGACCGTGATTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. {ECO:0000256|SAAS:SAAS00459874}.

Family

ScpB family

GO

cytoplasm GO:0005737 cellular_component
cell division GO:0051301 biological_process
chromosome separation GO:0051304 biological_process

InterPro

UniProt: I6XCB2
GenBank: Rv1710
EnsemblBacteria: Rv1710
Mycobrowser: Rv1710

Summary

Name: Segregation and condensation protein B
Family: ScpB family
Protein Sequence: MTEHMPEHDPSYGIPDIAEPAELDADELKRVLEALLLVIDTPVTADALAAATEQPVYRVAAKLQLMADELTGRDSGIDLRHTSEGWRMYTRARFAPYVEKLLLDGARTKLTRAALETLAVVAYRQPVTRARVSAVRGVNVDAVMRTLLARGLITEVGTDADTGAVTFATTELFLERLGLTSLSELPDIAPLLPDVDTIDDLSESLDSEPRFIKLTGELASEQTLSFDVDRD
Mass: 25,277 Da
Length: 231 Aa

Rv1710 doesn't seem to be a targeted by any drug.

Rv1710 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.