Gene - combatTB X

Rv1754c

Type: protein_coding
Name: Rv1754c
Locus Name: Rv1754c
Product: Conserved protein
Functional Category: Conserved hypotheticals
Location: 1984979..1986670 (- strand)
Gene Length: 1691 bp
Nucleotides: ATGTACCGGTACCAAGTCCGAGTGCAGCAGCGCAGGTCGGAGATGAACAGATGGGTTGCGACACGGTCACGGAGGCATACCTATCAGTGGATCACTGATCACAAGAGTCCCAGAGATCACTATCGTCACATCAGCGAACTGCGGACGTCAATTGCAACGTCCAGCCCGGGAAGGTGTGACATGTCGCCGATTCCTCGAATCGTGTCGGTATCGCTGGCGTGGGCGGCCGCTATTGGACTCATGGTTCCAATAGGCCTGGCGCCACCAGCGATGGCGGCGCCGTGCAGCGGAGACGCCGCGAACGCTCCGCCGCCACCGAGCGCCATTGTGACCGACCCCGGGGCCACGGCGCTCGGCCCGGTACGACCTGGACACGGTCCGATACCGACCGGACGCAAGCCTCGCGGTGCCAACGACCGTGCACCGCTACCCAAGCTGGGTCCACTGATATCCGCATTGCTCAACCCGGGTGCTAGAAATGCCGCGCCGCTACAACAGCAAGCGCTAGTCCCCAGGGCCAATCCTGGGCCCAATCCGGCACCCAATCCGCCAGCCACGGGCCCACAACCCCCGAATGCCACTCAGCTAACTCCGAACCCAGCCCCAGCACCCGACCCTGCTCCGGCGGCGGCGCCGGATCCTGGTGCCACGCTCGCCGGGGCTACCACATCCCTCGCCGAGTGGGTGACCGGACCGGACAGCCCCAACAAGACCCTGGAACGCTTCGGCATCTCCGGGACCGACCTCGGAATTCCTTGGGATAACGGCGATCCCGCCAACCGTCAGGTGCTCATGATCTTCGGCGACACATTCGGCTACTGCGCTGTCGATGGCCATCAATGGCGATACAACACGCTGTTCCGCAGCCAAGACCGCGACCTGGGCAACGGAGTTCATGTGACATCCGGTGACGCTTCCAACAGATATTCCGGCTCACCGGTACGCCAACCGGGCTTCTCCAAACAGCTCATCAACAGCATCAAATGGGCGCGCGACGAGACGGGGATCATTCCGACCGCGGGCATCGCCGTCGGCAAAACCCAATACGTCAACTTCATGTCCATCAGGAATTGGGGCCGTGATGGGGAATGGACGACGAACTACTCGGGCATCGCGGTGTCCAAGGACAATGGTCAGACCTGGGGGGTCTTCCCGGGCACCATCCGCGCGTCCGGACCGGACAGCGGCGGAAAAGCCAGGTTCGTTCCGGGAAATGAGAACTTCCAGATGGGGGCGTACCTCAAGTCCAACGACGGTTACCTCTACTCGTTCGGGACCCCGCCCGGGCGAGGCGGTTCGGCATATCTGGCACGAGTTCCGCAGCGCTTTGTGCCCGACCTCACCAAGTACCAGTACTGGAACGGCGACTCGAACTCCTGGGTTCCAAACAAGCCGGACGCGGCAACACCCGTTATTCCGGGCCCGGTGGGCGAAATGTCCGTCCAATACAACACCTACCTCAAGCAATACCTGGCGCTCTACACCAACGGTATGAACGACGTGGTGGCAAGGACCGCGCCGGCTCCGCAAGGACCGTGGAGCGCAGAGCAAATGCTGGTGTCGTCATGGCAGATGCCCGGCGGCATCTACGCGCCGATGATGCATCCCTGGTCGACGGGCAAAGACGTCTACTTTAACCTGTCTTTGTGGTCGGCATACAACGTGATGTTGATGCACACCGTGCTGCCATA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR025442

UniProt: O06790
GenBank: Rv1754c
EnsemblBacteria: Rv1754c
Mycobrowser: Rv1754c

Summary

Name: Conserved protein
Family: Unknown
Protein Sequence: MYRYQVRVQQRRSEMNRWVATRSRRHTYQWITDHKSPRDHYRHISELRTSIATSSPGRCDMSPIPRIVSVSLAWAAAIGLMVPIGLAPPAMAAPCSGDAANAPPPPSAIVTDPGATALGPVRPGHGPIPTGRKPRGANDRAPLPKLGPLISALLNPGARNAAPLQQQALVPRANPGPNPAPNPPATGPQPPNATQLTPNPAPAPDPAPAAAPDPGATLAGATTSLAEWVTGPDSPNKTLERFGISGTDLGIPWDNGDPANRQVLMIFGDTFGYCAVDGHQWRYNTLFRSQDRDLGNGVHVTSGDASNRYSGSPVRQPGFSKQLINSIKWARDETGIIPTAGIAVGKTQYVNFMSIRNWGRDGEWTTNYSGIAVSKDNGQTWGVFPGTIRASGPDSGGKARFVPGNENFQMGAYLKSNDGYLYSFGTPPGRGGSAYLARVPQRFVPDLTKYQYWNGDSNSWVPNKPDAATPVIPGPVGEMSVQYNTYLKQYLALYTNGMNDVVARTAPAPQGPWSAEQMLVSSWQMPGGIYAPMMHPWSTGKDVYFNLSLWSAYNVMLMHTVLP
Mass: 60,608 Da
Length: 563 Aa

Rv1754c doesn't seem to be a targeted by any drug.

Rv1754c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.