Rv1767



Type
protein_coding
Name
Rv1767
Locus Name

Rv1767

Product

Conserved protein

Functional Category

Conserved hypotheticals

Location
2000074..2000433 (+ strand)
Gene Length
359 bp
Nucleotides
TGTCGGACCAGCCACGTCATCACCAGGTCCTCGACGACCTGCTGCCCCAACACCGCGCTCTACGTCACCAGATTCCCCAGGTGTACCAGCGATTTGTAGCCCTGGGCGACGCCGCGCTTACCGACGGCGCTCTCAGCCGCAAGGTCAAGGAGCTTGTGGCGCTGGCGATCGCGGTTGTGCAGGGGTGCGATGGCTGCGTCGCATCACACGCCCAAGCCGCGGTACGGGCCGGCGCTACAGCGCAAGAAGCCGCTGAGGCCATCGGGGTCACCATCTTGATGCACGGTGGACCGGCCACCATCCACGGTGCTCGTGCCTACGCGGCATTTTGCGAATTCGCTGACACAACGCCGTCCTAG
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. {ECO:0000256|SAAS:SAAS00088543}.
Family

AhpD family

GO
InterPro

UniProt
O06800
GenBank
Rv1767
EnsemblBacteria
Rv1767
Mycobrowser
Rv1767


Summary
Name
Alkyl hydroperoxide reductase AhpD (EC 1.11.1.15)
Family
AhpD family
Protein Sequence
MSDQPRHHQVLDDLLPQHRALRHQIPQVYQRFVALGDAALTDGALSRKVKELVALAIAVVQGCDGCVASHAQAAVRAGATAQEAAEAIGVTILMHGGPATIHGARAYAAFCEFADTTPS
Mass
12,491 Da
Length
119 Aa

Rv1767 doesn't seem to be a targeted by any drug.


Rv1767 doesn't seem to be involved in any pathway.


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.