Gene - combatTB X

Rv1770

Type: protein_coding
Name: Rv1770
Locus Name: Rv1770
Product: Conserved protein
Functional Category: Conserved hypotheticals
Location: 2003878..2005164 (+ strand)
Gene Length: 1286 bp
Nucleotides: TGGACGAGGCCCACCCGGCTCACCCGGCAGATGCGGGGCGGCCCGGTGGCCCAATTCAAGGCGCGCGAAGAGGAGCTGCCATGACACCGATCACCGCCCTGCCGACCGAGTTGGCGGCCATGCGCGAGGTAGTCGAGACGCTCGCACCCATTGAGCGTGCCGCGGGCGAGCCGGGTGAGCACAAGGCGGCCGAGTGGATCGTCGAGCGCCTGCGCACGGCGGGCGCGCAGGACGCGCGCATCGAGGAGGAGCAGTACCTCGACGGCTACCCGAGGCTGCACCTCAAGCTGTCGGTGATCGGGGTGGCGGCCGGCGTCGCGGGCCTGCTCAGCAGACGTTTGCGCATCCCCGCCGCGCTGGCCGGGGTGGGTGCGGGGCTGGCAATCGCCGACGATTGCGCCAACGGGCCGCGCATTGTGCGCAAACGAACGGAGACGCCCCGGACGACATGGAACGCGGTAGCCGAGGCCGGTGATCCTGCTGGTCAGCTAACAGTTGTTGTGTGCGCTCACCACGACGCCGCGCACAGCGGCAAGTTTTTCGAGGCTCATATTGAGGAGGTAATGGTCGAGCTGTTTCCCGGGATTGTGGAGCGCATCGACACGCAGCTGCCGAACTGGTGGGGGCCGATCCTCGCGCCCGCACTCGCCGGTGTCGGCGCCCTGCGCGGCAGCCGGCCGATGATGATCGCCGGAACGGTGGGTAGCGCCCTGGCCGCCGCTTTGTTCGCCGACATCGCGCGCAGTCCGGTCGTCCCCGGTGCCAACGACAATCTCTCCGCGGTTGCGCTGCTGGTCGCGCTGGCCGAGCGGCTGCGCGAGCGGCCGGTGAAGGGCGTGCGAGTGTTGCTCGTGTCCCTGGGGGCCGAGGAAACGTTGCAGGGCGGGATCTACGGGTTCCTGGCGCGACACAAACCCGAGCTGGACCGCGACCGCACATACTTCCTGAACTTCGACACCATCGGCTCACCCGAGCTCATCATGCTCGAGGGCGAGGGCCCGACGGTCATGGAGGACTACTTCTATCGGCCATTCCGGGATCTGGTCATCCGGGCGGCCGAGCGCGCCGACGCGCCGCTGCGGCGCGGCATCCGGTCGCGCAACAGTACCGACGCGGTGTTGATGAGCCGCGCCGGCTACCCGACCGCGTGCTTTGTGTCGATCAACCGGCACAAGTCGGTGGCCAATTACCACCTGATGTCCGATACACCTGAGAATCTCTGCTATGAGACGGTGTCCCACGCCGTCACCGTCGCCGAATCCGTGATCAGGGAGCTGGCCCGATGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

plasma membrane GO:0005886 cellular_component
aminopeptidase activity GO:0004177 molecular_function
proteolysis GO:0006508 biological_process

InterPro

IPR007484

UniProt: O06803
GenBank: Rv1770
EnsemblBacteria: Rv1770
Mycobrowser: Rv1770

Summary

Name: Conserved protein
Family: Unknown
Protein Sequence: MDEAHPAHPADAGRPGGPIQGARRGAAMTPITALPTELAAMREVVETLAPIERAAGEPGEHKAAEWIVERLRTAGAQDARIEEEQYLDGYPRLHLKLSVIGVAAGVAGLLSRRLRIPAALAGVGAGLAIADDCANGPRIVRKRTETPRTTWNAVAEAGDPAGQLTVVVCAHHDAAHSGKFFEAHIEEVMVELFPGIVERIDTQLPNWWGPILAPALAGVGALRGSRPMMIAGTVGSALAAALFADIARSPVVPGANDNLSAVALLVALAERLRERPVKGVRVLLVSLGAEETLQGGIYGFLARHKPELDRDRTYFLNFDTIGSPELIMLEGEGPTVMEDYFYRPFRDLVIRAAERADAPLRRGIRSRNSTDAVLMSRAGYPTACFVSINRHKSVANYHLMSDTPENLCYETVSHAVTVAESVIRELAR
Mass: 45,973 Da
Length: 428 Aa

Rv1770 doesn't seem to be a targeted by any drug.

Rv1770 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.