Gene - combatTB X

PE_PGRS34

Type: protein_coding
Name: PE_PGRS34
Locus Name: Rv1840c
Product: PE-PGRS family protein PE_PGRS34
Functional Category: Pe/ppe
Location: 2087971..2089518 (- strand)
Gene Length: 1547 bp
Nucleotides: ATGTCGTTTGTGGTGGCGGCCCCAGAAGTGGTGGTGGCGGCGGCGTCGGATTTGGCCGGCATCGGGTCGGCGATCGGCGCGGCGAATGCGGCTGCGGCCGTGCCCACGATGGGGGTGCTGGCCGCGGGCGCCGATGAGGTGTCGGCGGCTGTTGCGGATTTGTTCGGCGCGCACGCCCAGGCCTATCAGGCATTGAGTGCGCAGGCGGCGCTGTTTCACGAGCAGTTTGTGCATGCCATGACCGCCGGCGCGGGGGCCTATGCCGGTGCCGAGGCGGCGGACGCCGCCGCGCTGGACGTGCTCAACGGGCCGTTTCAGGCGTTGTTCGGCCGCCCGTTGATCGGTGATGGCGCCAATGGCGCGCCGGGACAGCCCGGCGGGCCCGGCGGGTTGCTGTACGGCAACGGCGGCAACGGCGGCAACGGCGGGATCGGCCAGCCCGGCGGCGCCGGTGGGGATGCAGGGTTGATCGGCAACGGCGGCAACGGTGGCATCGGCGGGCCCGGGGCGACCGGCCTTGCCGGTGGTGCCGGCGGGGTCGGCGGACTGCTCTTCGGCGACGGCGGCAACGGCGGTGCCGGCGGACTCGGTACCGGACCCGTCGGCGCTACCGGTGGGATCGGCGGGCCCGGTGGAGCCGCCGTCGGGCTGTTCGGCCATGGCGGGGCCGGCGGGGCCGGCGGGCTCGGCAAGGCCGGCTTCGCGGGCGGGGCCGGCGGCACCGGCGGCACCGGCGGACTGCTGTACGGCAACGGCGGCAACGGCGGCAATGTCCCATCGGGAGCCGCCGACGGCGGAGCGGGCGGTGACGCCCGGCTGATCGGCAACGGGGGCGACGGCGGCTCCGTCGGTGCCGCCCCCACCGGCATCGGCAACGGCGGCAACGGCGGCAACGGCGGGTGGCTGTACGGCGACGGCGGTTCCGGAGGCAGCACCCTGCAAGGTTTCAGCGACGGTGGTACCGGCGGTAACGCCGGGATGTTCGGCGACGGCGGTAACGGCGGGTTCAGCTTCTTCGATGGCAACGGCGGCGACGGCGGCACCGGCGGGACGCTGATCGGCAACGGCGGCGACGGCGGCAACAGCGTGCAAACCGACGGCTTTCTCCGAGGCCACGGCGGCGACGGCGGCAACGCCGTCGGGCTGATCGGCAACGGTGGCGCCGGAGGCGCCGGGTCCGCCGGTACCGGCGTCTTCGCCCCCGGCGGTGGCAGTGGCGGGAACGGAGGCAACGGCGCGCTGCTGGTCGGCAACGGTGGCGCCGGCGGCTCCGGTGGGCCAACCCAGATTCCCTCAGTCGCGGTACCCGTCACCGGCGCCGGCGGCACCGGGGGTAACGGCGGCACGGCCGGGTTGATCGGCAACGGTGGCAATGGCGGCGCCGCCGGCGTCAGCGGGGACGGCACCCCCGGCACCGGCGGTAACGGCGGCTACGCCCAGTTGATCGGCGACGGCGGCGACGGTGGGCCCGGCGACTCTGGCGGGCCGGGCGGCAGCGGCGGTACGGGCGGAACGCTGGCCGGCCAGAACGGGTCCCCCGGGGGATA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PE family, PGRS subfamily

GO

plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR000084

UniProt: P9WIF3
GenBank: Rv1840c
EnsemblBacteria: Rv1840c
Mycobrowser: Rv1840c

Summary

Name: Uncharacterized PE-PGRS family protein PE_PGRS34
Family: Mycobacterial PE family, PGRS subfamily
Protein Sequence: MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFGAHAQAYQALSAQAALFHEQFVHAMTAGAGAYAGAEAADAAALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGGLLYGNGGNGGNGGIGQPGGAGGDAGLIGNGGNGGIGGPGATGLAGGAGGVGGLLFGDGGNGGAGGLGTGPVGATGGIGGPGGAAVGLFGHGGAGGAGGLGKAGFAGGAGGTGGTGGLLYGNGGNGGNVPSGAADGGAGGDARLIGNGGDGGSVGAAPTGIGNGGNGGNGGWLYGDGGSGGSTLQGFSDGGTGGNAGMFGDGGNGGFSFFDGNGGDGGTGGTLIGNGGDGGNSVQTDGFLRGHGGDGGNAVGLIGNGGAGGAGSAGTGVFAPGGGSGGNGGNGALLVGNGGAGGSGGPTQIPSVAVPVTGAGGTGGNGGTAGLIGNGGNGGAAGVSGDGTPGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGGTGGTLAGQNGSPGG
Mass: 43,916 Da
Length: 515 Aa

Rv1840c doesn't seem to be a targeted by any drug.

Rv1840c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.