lldD2
- Type
- protein_coding
- Name
- lldD2
- Locus Name
-
Rv1872c
- Product
-
Possible L-lactate dehydrogenase (cytochrome) LldD2
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 2121907..2123151 (- strand)
- Gene Length
- 1244 bp
- Nucleotides
-
ATGGCGGTCAACCGGCGAGTGCCCAGAGTGCGCGATCTGGCACCCCTGCTCCAGTTCAACAGGCCGCAGTTCGACACCTCCAAGCGCCGCCTGGGCGCCGCGCTGACCATCCAGGACCTGCGACGCATTGCCAAACGGCGTACCCCTAGGGCGGCGTTCGACTACGCCGACGGGGGTGCCGAGGACGAACTGTCCATCGCGCGTGCTCGACAAGGGTTCCGCGACATCGAGTTTCACCCGACAATCCTGCGTGACGTCACCACCGTGTGCGCCGGCTGGAACGTCCTCGGTCAGCCCACCGTCTTGCCATTCGGGATCGCGCCAACCGGGTTCACCCGCTTGATGCACACCGAGGGCGAGATCGCCGGCGCGCGGGCGGCGGCCGCGGCTGGGATCCCGTTTTCGCTATCCACCCTGGCCACCTGTGCCATCGAAGACCTCGTCATCGCTGTGCCGCAGGGCCGCAAATGGTTCCAGCTGTATATGTGGCGTGATCGAGACCGCTCGATGGCATTGGTGCGGCGCGTCGCCGCCGCGGGATTTGACACCATGCTGGTCACGGTCGACGTCCCGGTCGCCGGTGCCCGGCTACGCGATGTCCGCAACGGGATGTCCATCCCGCCGGCGCTGACGCTGCGAACCGTTCTCGACGCGATGGGACACCCGCGGTGGTGGTTCGACTTGTTGACCACCGAACCGCTGGCCTTCGCTTCACTGGATCGCTGGCCTGGCACCGTCGGCGAGTACTTGAACACCGTGTTCGACCCCAGCCTCACCTTCGACGATTTGGCCTGGATCAAGTCGCAGTGGCCGGGCAAGCTCGTTGTCAAAGGGATCCAAACACTCGACGACGCCCGCGCCGTGGTGGACCGCGGCGTCGACGGCATCGTGTTGTCCAATCACGGCGGCCGCCAGCTTGACCGAGCCCCGGTACCCTTCCACCTGTTGCCCCACGTGGCACGCGAACTGGGCAAACACACCGAAATCCTGGTGGACACCGGCATCATGTCGGGCGCCGATATCGTCGCGGCGATCGCGTTGGGGGCACGGTGCACGCTGATCGGGCGGGCCTACCTTTACGGGCTGATGGCCGGTGGTGAGGCGGGCGTCAACCGCGCGATCGAGATCCTTCAGACAGGTGTGATCCGGACCATGCGGCTACTGGGCGTGACCTGCCTTGAGGAGCTGTCACCTCGGCACGTGACACAACTGCGGCGGCTCGGCCCTATCGGGGCACCAACGTG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
FMN-dependent alpha-hydroxy acid dehydrogenase family
- GO
-
- lactate oxidation GO:0019516 biological_process
- FMN binding GO:0010181 molecular_function
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- L-lactate dehydrogenase activity GO:0004459 molecular_function
- InterPro
Summary
- Name
- Putative L-lactate dehydrogenase (EC 1.1.-.-)
- Family
- FMN-dependent alpha-hydroxy acid dehydrogenase family
- Protein Sequence
-
MAVNRRVPRVRDLAPLLQFNRPQFDTSKRRLGAALTIQDLRRIAKRRTPRAAFDYADGGAEDELSIARARQGFRDIEFHPTILRDVTTVCAGWNVLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQGRKWFQLYMWRDRDRSMALVRRVAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRTVLDAMGHPRWWFDLLTTEPLAFASLDRWPGTVGEYLNTVFDPSLTFDDLAWIKSQWPGKLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVARELGKHTEILVDTGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLGVTCLEELSPRHVTQLRRLGPIGAPT
- Mass
- 45,342 Da
- Length
- 414 Aa
Rv1872c doesn't seem to be a targeted by any drug.
-
-
Pyruvate metabolism mtu00620
mtu00620PATHWAY_MAP mtu00620 Pyruvate metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.