Gene - combatTB X

cinA

Type: protein_coding
Name: cinA
Locus Name: Rv1901
Product: Probable CinA-like protein CinA
Functional Category: Virulence, detoxification, adaptation
Location: 2147662..2148954 (+ strand)
Gene Length: 1292 bp
Nucleotides: TGGCGGTGAGCGCACGTGCGGGCATCGTGATCACCGGAACCGAGGTCCTGACCGGGCGGGTCCAAGACCGCAACGGCCCCTGGATCGCCGATCGGCTCCTGGAGCTCGGGGTCGAGTTGGCACACATCACGATCTGCGGCGACCGTCCCGCCGACATCGAGGCACAGCTGCGATTCATGGCTGAGCAGGGTGTGGACCTGATCGTCACCAGCGGCGGCCTGGGGCCGACCGCCGACGATATGACCGTCGAGGTGGTGGCGCGCTATTGCGGGCGCGAGCTGGTGCTGGACGACGAGCTGGAGAACAGGATCGCCAACATCCTCAAGAAGCTGATGGGGCGAAATCCCGCTATTGAACCCGCCAACTTCGACTCCATACGCGCCGCCAACCGCAAACAGGCCATGATTCCGGCCGGATCGCAAGTGATCGATCCGGTGGGCACCGCCCCCGGTCTGGTTGTGCCGGGACGGCCAGCGGTGATGGTGCTTCCCGGGCCACCGCGCGAGCTGCAGCCGATATGGAGCAAGGCCATCCAGACGGCTCCGGTACAGGATGCGATTGCCGGCCGGACGACCTACCGACAGGAGACCATCCGGATCTTCGGCCTGCCGGAGTCTTCTCTGGCCGACACACTGCGTGACGCCGAGGCAGCCATCCCGGGTTTTGACTTAGTCGAGATCACCACCTGCCTGCGGCGCGGCGAGATTGAAATGGTCACTCGCTTTGAACCGAACGCCGCGCAAGTGTACACGCAATTGGCACGGTTATTGCGCGACCGGCACGGCCACCAGGTCTATTCGGAAGACGGTGCGTCCGTGGACGAGCTGGTCGCAAAATTGCTAACTGGCCGCCGGATAGCGACCGCCGAATCCTGCACCGCAGGGTTGCTGGCGGCACGGCTCACCGACCGGCCCGGGTCGTCCAAGTACGTGGCGGGCGCAGTGGTGGCCTACTCTAACGAGGCGAAGGCACAGCTTCTCGGTGTGGATCCGGCGCTGATCGAGGCCCACGGGGCGGTTTCCGAGCCGGTCGCCCAGGCAATGGCAGCGGGGGCGCTGCAAGGCTTCGGCGCCGACACCGCCACCGCGATCACCGGAATTGCGGGTCCGAGTGGGGGAACGCCGGAAAAGCCTGTGGGAACAGTGTGCTTCACCGTCCTGCTGGACGATGGCCGAACAACCACCCGAACCGTGCGGCTGCCCGGGAACCGGTCAGACATTAGGGAGCGCTCGACGACTGTGGCGATGCACCTGCTGCGGCGCACCCTGAGCGGTATCCCGGGCTCACCCTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

CinA family

GO

plasma membrane GO:0005886 cellular_component

InterPro

UniProt: P9WPE3
GenBank: Rv1901
EnsemblBacteria: Rv1901
Mycobrowser: Rv1901

Summary

Name: CinA-like protein
Family: CinA family
Protein Sequence: MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP
Mass: 45,512 Da
Length: 430 Aa

Rv1901 doesn't seem to be a targeted by any drug.

Rv1901 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.