lppC
- Type
- protein_coding
- Name
- lppC
- Locus Name
-
Rv1911c
- Product
-
Probable lipoprotein LppC
- Functional Category
-
Cell wall and cell processes
- Location
- 2157382..2157987 (- strand)
- Gene Length
- 605 bp
- Nucleotides
-
ATGACGAGCACACTTCACCGAACCCCATTAGCCACCGCGGGGCTGGCGCTCGTAGTGGCGCTGGGTGGCTGCGGGGGCGGGGGCGGTGACAGTCGAGAGACACCGCCATACGTGCCGAAAGCGACGACCGTCGACGCAACAACGCCGGCGCCGGCCGCCGAGCCACTGACGATCGCCAGTCCCATGTTCGCCGACGGCGCCCCGATCCCGGTGCAATTCAGCTGCAAGGGGGCCAACGTGGCGCCACCGTTGACGTGGTCGTCGCCCGCGGGCGCAGCCGAACTGGCACTCGTCGTCGATGACCCCGACGCGGTCGGCGGACTGTACGTGCACTGGATCGTGACCGGAATCGCCCCTGGCTCTGGCAGCACGGCGGATGGTCAGACTCCTGCTGGTGGGCACAGCGTGCCGAATTCTGGTGGTCGGCAAGGATACTTCGGTCCATGCCCGCCGGCGGGCACCGGGACACACCACTACCGGTTTACCCTCTACCACCTTCCTGTCGCGCTCCAGCTGCCACCGGGAGCCACGGGAGTCCAAGCGGCACAGGCGATAGCACAGGCCGCCAGCGGACAGGCCCGGCTCGTCGGCACATTCGAAGGCTG
- Drug Resistance
- Mutations
- Function
- Probably involved in bacterial recognition and uptake by its host (human) (PubMed:25041568). {ECO:0000269|PubMed:25041568}.
- Family
-
UPF0098 family
- GO
-
- cell surface GO:0009986 cellular_component
- cell wall GO:0005618 cellular_component
- extracellular region GO:0005576 cellular_component
- plasma membrane GO:0005886 cellular_component
- InterPro
Summary
- Name
- Putative lipoprotein LppC (UPF0098 protein Rv1911c)
- Family
- UPF0098 family
- Protein Sequence
-
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
- Mass
- 19,798 Da
- Length
- 201 Aa
Rv1911c doesn't seem to be a targeted by any drug.
Rv1911c doesn't seem to be involved in any pathway.
- Specific interaction between Mycobacterium tuberculosis lipoprotein-derived peptides and target cells inhibits mycobacterial entry in vitro.
- Chem Biol Drug Des. 2014 Dec;84(6):626-41. doi: 10.1111/cbdd.12365. Epub 2014 Jul 10.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.