Rv1931c
- Type
- protein_coding
- Name
- Rv1931c
- Locus Name
-
Rv1931c
- Product
-
Probable transcriptional regulatory protein
- Functional Category
-
Regulatory proteins
- Location
- 2182460..2183239 (- strand)
- Gene Length
- 779 bp
- Nucleotides
-
GTGGTTATCGTGGGATTCCCCGGCGACCCCGTCGACACCGTGATCCTGCCCGGTGGCGCCGGAGTCGATGCCGCACGGTCCGAACCGGCCCTCATCGACTGGGTCAAAGCCGTCTCCGGCACCGCCCGCCGCGTCGTCACCGTGTGCACGGGCGCGTTTCTTGCGGCCGAAGCGGGGTTGTTGGGACGGACACCGAGCGACGACGCACTGGGCCTTTGCCGAACATTTCGCCCGCGAATTTCCGGCCGTTCGGGTCGATGCCGACCCGATCTTCATGCGCAGTTCGCAGAAGGTGTGGACCGCGGCTGGAGTCACCGCCGGCATCGACCTCGCGCTGGCACTGGTCGAAGACGACCACGGCACCGAGATTGCCCAGACGGTTGCCCGCTGGCTCGTCCTGTATCTGCGCCGACCCGGTGGGCAGACCCAGTTCGCGGCTCCGGTGTGGATGCCACGCGCCAAACGGACCTCGATCCGCCGGGTGCAGGAGGCCATCGAGGCCGAGCCGGGGGCGCGCACCGCATCGGCGAACTGGCTCAACGTGCGGCCATGAGCCCGCGTCATTTCACTCGGGTGTTCAGCGACGAGGTCGGCGAGGCGCCCGGCCGGTACGTCGAACGCATCCGCACCGAGGCTGCGCGCCGCCAGTTGGAGGAGACCCACGACACCGTGGTGGCAATTGCCGCCCGATGCGGCTTCGGGACCGCGGAAACCATGCGCCGCAGCTTCATTCGCCGCGTCGGGATATCACCCGACCAATACCGCAAAGCCTTCGCCTG
- Drug Resistance
- Mutations
- Function
- Controls the expression of genes important for virulence. {ECO:0000269|PubMed:15322050}.
- Family
-
Unknown
- GO
-
- pathogenesis GO:0009405 biological_process
- DNA-binding transcription factor activity GO:0003700 molecular_function
- plasma membrane GO:0005886 cellular_component
- sequence-specific DNA binding GO:0043565 molecular_function
- InterPro
Summary
- Name
- HTH-type transcriptional regulator Rv1931c
- Family
- Unknown
- Protein Sequence
-
MVIVGFPGDPVDTVILPGGAGVDAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGLCRTFRPRISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA
- Mass
- 27,996 Da
- Length
- 259 Aa
Rv1931c doesn't seem to be a targeted by any drug.
Rv1931c doesn't seem to be involved in any pathway.
- Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis.
- Microbiology. 2009 Jul;155(Pt 7):2245-55. doi: 10.1099/mic.0.027086-0. Epub 2009 Apr 23.
- The AraC family transcriptional regulator Rv1931c plays a role in the virulence of Mycobacterium tuberculosis.
- Infect Immun. 2004 Sep;72(9):5483-6. doi: 10.1128/IAI.72.9.5483-5486.2004.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.